The oral microbiome: Role of key organisms and complex networks in oral health and disease

L Sedghi, V DiMassa, A Harrington… - Periodontology …, 2021 - Wiley Online Library
States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

The dental plaque biofilm matrix

NS Jakubovics, SD Goodman… - Periodontology …, 2021 - Wiley Online Library
The extracellular matrix is a critical component of microbial biofilms, such as dental plaque,
maintaining the spatial arrangement of cells and coordinating cellular functions throughout …

Ecology of the oral microbiome: beyond bacteria

JL Baker, B Bor, M Agnello, W Shi, X He - Trends in microbiology, 2017 - cell.com
Although great strides have been made in understanding the complex bacterial community
inhabiting the human oral cavity, for a variety of (mainly technical) reasons the ecological …

Candida albicans promotes tooth decay by inducing oral microbial dysbiosis

Q Du, B Ren, J He, X Peng, Q Guo, L Zheng… - The ISME …, 2021 - academic.oup.com
Candida albicans has been detected in root carious lesions. The current study aimed to
explore the action of this fungal species on the microbial ecology and the pathogenesis of …

Current state and challenges of the global outcomes of dental caries research in the meta-omics era

DG Moussa, P Ahmad, TA Mansour… - Frontiers in Cellular and …, 2022 - frontiersin.org
Despite significant healthcare advances in the 21st century, the exact etiology of dental
caries remains unsolved. The past two decades have witnessed a tremendous growth in our …

Saccharibacteria (TM7) in the human oral microbiome

B Bor, JK Bedree, W Shi… - Journal of dental …, 2019 - journals.sagepub.com
Bacteria from the Saccharibacteria phylum (formerly known as TM7) are ubiquitous
members of the human oral microbiome and are part of the Candidate Phyla Radiation …

Addition of cariogenic pathogens to complex oral microflora drives significant changes in biofilm compositions and functionalities

Y Liu, SG Daniel, HE Kim, H Koo, J Korostoff, F Teles… - Microbiome, 2023 - Springer
Background Dental caries is a microbe and sugar-mediated biofilm-dependent oral disease.
Of particular significance, a virulent type of dental caries, known as severe early childhood …

Precision-guided antimicrobial peptide as a targeted modulator of human microbial ecology

L Guo, JS McLean, Y Yang, R Eckert… - Proceedings of the …, 2015 - National Acad Sciences
One major challenge to studying human microbiome and its associated diseases is the lack
of effective tools to achieve targeted modulation of individual species and study its …

Polymicrobial aggregates in human saliva build the oral biofilm

A Simon-Soro, Z Ren, BP Krom, MA Hoogenkamp… - MBio, 2022 - Am Soc Microbiol
Biofilm community development has been established as a sequential process starting from
the attachment of single cells on a surface. However, microorganisms are often found as …

Effect of UV-photofunctionalization on oral bacterial attachment and biofilm formation to titanium implant material

ED de Avila, BP Lima, T Sekiya, Y Torii, T Ogawa… - Biomaterials, 2015 - Elsevier
Bacterial biofilm infections remain prevalent reasons for implant failure. Dental implant
placement occurs in the oral environment, which harbors a plethora of biofilm-forming …