[HTML][HTML] Cholesterol-induced toxicity: An integrated view of the role of cholesterol in multiple diseases

Y Song, J Liu, K Zhao, L Gao, J Zhao - Cell metabolism, 2021 - cell.com
High levels of cholesterol are generally considered to be associated with atherosclerosis. In
the past two decades, however, a number of studies have shown that excess cholesterol …

[PDF][PDF] Role of cholesterol‐associated steatohepatitis in the development of NASH

CL Horn, AL Morales, C Savard… - Hepatology …, 2022 - Wiley Online Library
The rising prevalence of nonalcoholic fatty liver disease (NAFLD) and NAFLD‐related
cirrhosis in the United States and globally highlights the need to better understand the …

Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis

H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment

ME Ertunc, GS Hotamisligil - Journal of lipid research, 2016 - ASBMB
Lipids encompass a wide variety of molecules such as fatty acids, sterols, phospholipids,
and triglycerides. These molecules represent a highly efficient energy resource and can act …

Inflammation and lipid signaling in the etiology of insulin resistance

CK Glass, JM Olefsky - Cell metabolism, 2012 - cell.com
Inflammation and lipid signaling are intertwined modulators of homeostasis and immunity. In
addition to the extensively studied eicosanoids and inositol phospholipids, emerging studies …

[HTML][HTML] Recent insights on the role of cholesterol in non-alcoholic fatty liver disease

G Arguello, E Balboa, M Arrese, S Zanlungo - Biochimica et Biophysica …, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of hepatic
histopathological changes ranging from non-inflammatory intracellular fat deposition to non …

Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis

G Musso, R Gambino, M Cassader - Progress in lipid research, 2013 - Elsevier
Emerging experimental and human evidence has linked altered hepatic cholesterol
homeostasis and free cholesterol (FC) accumulation to the pathogenesis of non-alcoholic …

Lung adenocarcinoma distally rewires hepatic circadian homeostasis

S Masri, T Papagiannakopoulos, K Kinouchi, Y Liu… - Cell, 2016 - cell.com
The circadian clock controls metabolic and physiological processes through finely tuned
molecular mechanisms. The clock is remarkably plastic and adapts to exogenous" …

Disturbances in cholesterol homeostasis and non-alcoholic fatty liver diseases

P Malhotra, RK Gill, S Saksena, WA Alrefai - Frontiers in Medicine, 2020 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a major health problem associated with obesity
and other features of the metabolic syndrome including insulin resistance and dyslipidemia …

The pathogenesis and pathophysiology of gestational diabetes mellitus: Deductions from a three-part longitudinal metabolomics study in China

KP Law, H Zhang - Clinica Chimica Acta, 2017 - Elsevier
Gestational diabetes mellitus (GDM) is a form of diabetes that is first recognised during
pregnancy, with no evidence of pre-existing type 1 or type 2 diabetes. The prevalence of …