Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …

We present an analysis of over 1,100 of the∼ 10,000 predicted proteins encoded by the
genome sequence of the filamentous fungus Neurospora crassa. Seven major areas of …

The establishment of cell polarity is critical for the development of many organisms and for
the function of many cell types. A large number of studies of diverse organisms from yeast to …

Filamentous fungi are a large and evolutionarily successful group of organisms of enormous
ecological importance (27, 114). Fungi also have a considerable impact on our economy …

Fungal hyphae extend by apical growth. This process involves the polarized traffic of
secretory vesicles to the Spitzenkörper (SPK) and their subsequent distribution to specific …

The high capacity of the secretion machinery of filamentous fungi has been widely exploited
for the production of homologous and heterologous proteins; however, our knowledge of the …

Streptomycetes grow by cell wall extension at hyphal tips. The molecular basis for such
polar growth in prokaryotes is largely unknown. It is reported here that DivIVASC, the …

Newly synthesized membrane proteins are transported by fast axonal flow to their targets
such as the plasma membrane and synaptic vesicles. However, their transporting vesicles …

One kind of the most extremely polarized cells in nature are the indefinitely growing hyphae
of filamentous fungi. A continuous flow of secretion vesicles from the hyphal cell body to the …

MYO2 encodes a type V myosin heavy chain needed for the targeting of vacuoles and
secretory vesicles to the growing bud of yeast. Here we describe new myo2 alleles …