Oral isotretinoin and its uses in dermatology: a review

A Paichitrojjana, A Paichitrojjana - Drug Design, Development and …, 2023 - Taylor & Francis
Abstract In 1982, the Food and Drug Administration (FDA) of the United States of America
approved isotretinoin (13-cis-retinoic acid), a retinoid derivative of vitamin A, to treat severe …

Optimizing isotretinoin treatment of acne: update on current recommendations for monitoring, dosing, safety, adverse effects, compliance, and outcomes

MN Landis - American journal of clinical dermatology, 2020 - Springer
Acne vulgaris is the most common skin disease treated by dermatologists. It can be severe
and result in permanent scars. Isotretinoin is the most effective treatment for acne and has …

High-dose isotretinoin treatment and the rate of retrial, relapse, and adverse effects in patients with acne vulgaris

RC Blasiak, CR Stamey, CN Burkhart… - JAMA …, 2013 - jamanetwork.com
Importance Isotretinoin is the most effective treatment for acne. The ideal dosing regimen is
unknown. Objective To determine the rates of relapse of acne vulgaris and retrial of …

[HTML][HTML] Oral isotretinoin in different dose regimens for acne vulgaris: a randomized comparative trial

US Agarwal, RK Besarwal, K Bhola - Indian Journal of Dermatology …, 2011 - ijdvl.com
Background: Oral isotretinoin is recommended for severe nodulocystic acne in the doses of
1-2 mg/kg/day which is usually associated with higher incidence of adverse effects. To …

Low‐dose oral isotretinoin therapy in lichen planus pigmentosus: an open‐label non‐randomized prospective pilot study

SK Muthu, T Narang, UN Saikia… - International Journal …, 2016 - Wiley Online Library
Background Lichen planus pigmentosus (LPP) is a cosmetically distressing pigmentary
disorder often posing a therapeutic challenge. Isotretinoin has been shown to be effective in …

Low‐dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study

E Bagatin, LRS Guadanhim… - International Journal …, 2014 - Wiley Online Library
Background Oral isotretinoin (ISO) is the only drug which promotes prolonged remission or
cure of severe acne. It also has other properties, supporting its use for non‐acne indications …

Treatment of plane warts with a low‐dose oral isotretinoin

HR Al-Hamamy, HA Salman… - International Scholarly …, 2012 - Wiley Online Library
Objective. To assess the efficacy of a low‐dose oral isotretinoin in the treatment of plane
warts. Patients and Methods. Thirty‐one patients with recalcitrant facial plane warts were …

Concomitant use of 1,550-nm nonablative fractional laser with low-dose isotretinoin for the treatment of acne vulgaris in Asian patients: a randomized split-face …

J Xia, G Hu, D Hu, S Geng, W Zeng - Dermatologic Surgery, 2018 - journals.lww.com
BACKGROUND Nonablative fractional laser (NAFL) has been shown to improve the
appearance of inflammatory acne and acne scars. Isotretinoin is effective for the treatment of …

A randomized comparative trial of two low-dose oral isotretinoin regimens in moderate to severe acne vulgaris

DR Dhaked, RS Meena, A Maheshwari… - Indian Dermatology …, 2016 - journals.lww.com
Background: Oral isotretinoin is highly effective in all forms and grades of acne, even in
lower dosages (< 0.5 mg/kg/day). There is a paucity of comparative data on the various low …

Decreased ovarian reserve in female Sprague–Dawley rats induced by isotretinoin (retinoic acid) exposure

R Abali, MA Yuksel, C Aktas, C Celik, S Guzel… - Reproductive …, 2013 - Elsevier
Isotretinoin is a retinoid widely used for the treatment of severe nodulocystic acne. Although
it has broad side effects, there is no well-designed study about its effects on the ovary. This …