Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications

A Wicki, D Witzigmann, V Balasubramanian… - Journal of controlled …, 2015 - Elsevier
Cancer is a leading cause of death worldwide. Currently available therapies are inadequate
and spur demand for improved technologies. Rapid growth in nanotechnology towards the …

Porous silicon nanoparticles for nanomedicine: preparation and biomedical applications

HA Santos, E Mäkilä, AJ Airaksinen, LM Bimbo… - …, 2014 - Taylor & Francis
The research on porous silicon (PSi) materials for biomedical applications has expanded
greatly since the early studies of Leigh Canham more than 25 years ago. Currently, PSi …

[HTML][HTML] Acoustofluidics for simultaneous nanoparticle-based drug loading and exosome encapsulation

Z Wang, J Rich, N Hao, Y Gu, C Chen, S Yang… - Microsystems & …, 2022 - nature.com
Nanocarrier and exosome encapsulation has been found to significantly increase the
efficacy of targeted drug delivery while also minimizing unwanted side effects. However, the …

Multifunctional porous silicon nanoparticles for cancer theranostics

CF Wang, MP Sarparanta, EM Mäkilä, MLK Hyvönen… - Biomaterials, 2015 - Elsevier
Nanomaterials provide a unique platform for the development of theranostic systems that
combine diagnostic imaging modalities with a therapeutic payload in a single probe. In this …

Exploiting mesoporous silica nanoparticles as versatile drug carriers for several routes of administration

RM Sábio, AB Meneguin, AM dos Santos… - Microporous and …, 2021 - Elsevier
The exploitation of mesoporous silica nanoparticles (MSNs) as drug delivery systems has
grown exponentially due to their remarkable tunable properties, such as high surface area …

Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles

D Liu, LM Bimbo, E Mäkilä, F Villanova… - Journal of Controlled …, 2013 - Elsevier
Nanoparticulate drug delivery systems offer remarkable opportunities for clinical treatment.
However, there are several challenges when they are employed to deliver multiple …

Porous silicon nanoparticles as efficient sensitizers for sonodynamic therapy of cancer

LA Osminkina, AL Nikolaev, AP Sviridov… - Microporous and …, 2015 - Elsevier
Luminescent porous silicon nanoparticles with mean size of about 100 nm were covered by
biodegradable polymer (dextran) and were investigated as potential sensitizers for …

Review of the mechanism of nanocarriers and technological developments in the field of nanoparticles for applications in cancer theragnostics

N Shreyash, M Sonker, S Bajpai… - ACS Applied Bio …, 2021 - ACS Publications
Cancer cannot be controlled by the usage of drugs alone, and thus, nanotechnology is an
important technique that can provide the drug with an impetus to act more effectively. There …

Porous silicon for drug delivery applications and theranostics: recent advances, critical review and perspectives

T Kumeria, SJP McInnes, S Maher… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Porous silicon (pSi) engineered by electrochemical etching has been used as a
drug delivery vehicle to address the intrinsic limitations of traditional therapeutics …

Chitosan-modified porous silicon microparticles for enhanced permeability of insulin across intestinal cell monolayers

N Shrestha, MA Shahbazi, F Araújo, H Zhang… - Biomaterials, 2014 - Elsevier
Porous silicon (PSi) based particulate systems are emerging as an important drug delivery
system due to its advantageous properties such as biocompatibility, biodegradability and …