The promise of adolescence: Realizing opportunity for all youth

EP Backes, RJ Bonnie - 2019 - books.google.com
Adolescenceâ€" beginning with the onset of puberty and ending in the mid-20sâ€" is a
critical period of development during which key areas of the brain mature and develop …

Harmonizing the neurobiology and treatment of obsessive-compulsive disorder

WK Goodman, EA Storch… - American Journal of …, 2021 - Am Psychiatric Assoc
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling
disorder. The only established first-line treatments for OCD are exposure and response …

Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation

H Lui, J Zhang, SR Makinson, MK Cahill, KW Kelley… - Cell, 2016 - cell.com
Microglia maintain homeostasis in the brain, but whether aberrant microglial activation can
cause neurodegeneration remains controversial. Here, we use transcriptome profiling to …

Obsessive–compulsive disorder: an integrative genetic and neurobiological perspective

DL Pauls, A Abramovitch, SL Rauch… - Nature Reviews …, 2014 - nature.com
Obsessive–compulsive disorder (OCD) is characterized by repetitive thoughts and
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …

Resting-state functional connectivity in normal brain aging

LK Ferreira, GF Busatto - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
The world is aging and, as the elderly population increases, age-related cognitive decline
emerges as a major concern. Neuroimaging techniques, such as functional magnetic …

Error processing and inhibitory control in obsessive-compulsive disorder: a meta-analysis using statistical parametric maps

LJ Norman, SF Taylor, Y Liu, J Radua, Y Chye… - Biological …, 2019 - Elsevier
Background Error processing and inhibitory control enable the adjustment of behaviors to
meet task demands. Functional magnetic resonance imaging studies report brain activation …

Abnormal resting-state functional connectivity in patients with obsessive-compulsive disorder: A systematic review and meta-analysis

J Liu, L Cao, H Li, Y Gao, X Bu, K Liang, W Bao… - Neuroscience & …, 2022 - Elsevier
Obsessive-compulsive disorder (OCD) displays widespread disruption across brain regions
revealed by resting-state functional connectivity (rsFC) with inconsistent results between …

Global resting-state functional magnetic resonance imaging analysis identifies frontal cortex, striatal, and cerebellar dysconnectivity in obsessive-compulsive disorder

A Anticevic, S Hu, S Zhang, A Savic, E Billingslea… - Biological …, 2014 - Elsevier
Background Obsessive-compulsive disorder (OCD) is associated with regional hyperactivity
in cortico-striatal circuits. However, the large-scale patterns of abnormal neural connectivity …

Obsessive-compulsive disorder

WK Goodman, DE Grice, KAB Lapidus… - Psychiatric …, 2014 - psych.theclinics.com
Obsessive-compulsive disorder (OCD) is a common, typically chronic disorder marked by
intrusive and disturbing thoughts (obsessions) and repetitive behaviors (compulsions) that …

Brain corticostriatal systems and the major clinical symptom dimensions of obsessive-compulsive disorder

BJ Harrison, J Pujol, N Cardoner, J Deus, P Alonso… - Biological …, 2013 - Elsevier
BACKGROUND: Functional neuroimaging studies have provided consistent support for the
idea that obsessive-compulsive disorder (OCD) is associated with disturbances of brain …