Wound healing occurs as a response to disruption of the epidermis and dermis. It is an
intricate and well-orchestrated response with the goal to restore skin integrity and function …

Hypertrophic scars and keloids can have significant detrimental effects on patients both
psychosocially and functionally. A careful identification of patient risk factors and a …

Hypertrophic scar (HS) considerably affects the appearance and causes tissue dysfunction
in patients. The low bioavailability of 5-fluorouracil poses a challenge for HS treatment. Here …

Background: Wound healing is a complicated process involving multiple cell components
and can help the re-establishment of the skin's barrier function. Previous studies have …

We have previously demonstrated that RACK1, which expression is under steroid hormone
control, plays an important role in the activation of immune cells and its expression can be …

A keloid is a fibroproliferative disorder of unknown etiopathogenesis that requires ill-defined
treatment. Existing evidence indicates that the immune system plays an important role in the …

Photodynamic therapy (PDT) is widely used for the treatment of hypertrophic scars in clinical
practice. However, the low transdermal delivery of photosensitizers in scar tissue and …

Background Mesenchymal stem cell-derived exosomes (MSC-exo) have been shown to
have significant potential in wound healing and scar relief processes. According to reports …

Hypertrophic scars continue to be a major burden, especially after burns. Persistent
inflammation during wound healing appears to be the precipitating aspect in pathologic …

Hypertrophic scar (HS) is a chronic inflammatory skin disease characterized by excessive
deposition of extracellular matrix, but the exact mechanisms related to its formation remain …