Molecular mechanisms and therapeutic potential of lithium in Alzheimer's disease: repurposing an old class of drugs
Y Shen, M Zhao, P Zhao, L Meng, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive decline and memory loss. Despite advances in understanding the …
cognitive decline and memory loss. Despite advances in understanding the …
Tau in neurodegenerative diseases: molecular mechanisms, biomarkers, and therapeutic strategies
The deposition of abnormal tau protein is characteristic of Alzheimer's disease (AD) and a
class of neurodegenerative diseases called tauopathies. Physiologically, tau maintains an …
class of neurodegenerative diseases called tauopathies. Physiologically, tau maintains an …
Evaluation of potential human health risks associated with Li and their relationship with Na, K, Mg, and Ca in Romania's nationwide drinking water
Background Increasing lithium (Li) demand worldwide due to its properties and role in
renewable energy will raise water reservoir pollution and side effects on human health …
renewable energy will raise water reservoir pollution and side effects on human health …
Efficacy of brain stimulation therapies across psychiatric, movement, and cognitive disorders: an umbrella review synthesizing meta-analyses of randomized controlled …
Z Zu, F Chen, L Yang, W Wei, M Zhang, L Huang… - …, 2025 - thelancet.com
Background Brain stimulation therapy (BST) has significant potential in treating psychiatric,
movement, and cognitive disorders. Given the high prevalence of comorbidities among …
movement, and cognitive disorders. Given the high prevalence of comorbidities among …
[HTML][HTML] SARS-CoV-2 Infection and Alpha-Synucleinopathies: Potential Links and Underlying Mechanisms
JA Motyl, G Gromadzka, GA Czapski… - International Journal of …, 2024 - mdpi.com
Alpha-synuclein (α-syn) is a 140-amino-acid, intrinsically disordered, soluble protein that is
abundantly present in the brain. It plays a crucial role in maintaining cellular structures and …
abundantly present in the brain. It plays a crucial role in maintaining cellular structures and …
[HTML][HTML] Lithium Ions as Modulators of Complex Biological Processes: The Conundrum of Multiple Targets, Responsiveness and Non-Responsiveness, and the …
DA Hart - Biomolecules, 2024 - mdpi.com
Lithium is one of the lightest elements on Earth and it has been in the environment since the
formation of the galaxy. While a common element, it has not been found to be an essential …
formation of the galaxy. While a common element, it has not been found to be an essential …
[HTML][HTML] Intranasal Delivery of Lithium Salt Suppresses Inflammatory Pyroptosis in the brain and Ameliorates Memory Loss and Depression-like Behavior in 5XFAD …
P Bhuiyan, W Zhang, G Liang, B Jiang, R Vera… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Alzheimer's disease (AD) is a devastating neurodegenerative disease (AD)
and has no treatment that can cure or halt the disease progression. This study explored the …
and has no treatment that can cure or halt the disease progression. This study explored the …
[图书][B] Predictors of severe kidney disease in long-term lithium treatment
M Golic - 2024 - gupea.ub.gu.se
The thesis aims to advance the understanding of severe chronic kidney disease in lithium-
treated patients through four observational studies in which subjects were recruited from the …
treated patients through four observational studies in which subjects were recruited from the …
[PDF][PDF] Intranasal Lithium Chloride Nanoparticles Inhibit In-flammatory Pyroptosis in Brains and Ameliorate Memory Loss and Depression Behavior in 5xFAD mice
P Bhuiyana, W Zhanga, G Lianga, B Jianga, R Veraa… - biorxiv.org
This study compares the changes in lithium concentrations in the brain and blood following
the administration of intranasal or oral lithium chloride (LiCl) dissolved in either Ryanodex …
the administration of intranasal or oral lithium chloride (LiCl) dissolved in either Ryanodex …
[引用][C] Bone health impairment in childhood cancer: from preclinical studies to clinical insights
L Velentza - 2024 - Inst för kvinnors och barns hälsa …