[HTML][HTML] EMT mechanism in breast cancer metastasis and drug resistance: Revisiting molecular interactions and biological functions

M Hashemi, HZ Arani, S Orouei, S Fallah… - Biomedicine & …, 2022 - Elsevier
One of the malignant tumors in women that has involved both developed and developing
countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate …

N6-methyladenosine reader YTHDF family in biological processes: structures, roles, and mechanisms

L Chen, Y Gao, S Xu, J Yuan, M Wang, T Li… - Frontiers in …, 2023 - frontiersin.org
As the most abundant and conserved internal modification in eukaryote RNAs, N6-
methyladenosine (m6A) is involved in a wide range of physiological and pathological …

The structure and function of YTHDF epitranscriptomic m6A readers

V Sikorski, S Selberg, M Lalowski, M Karelson… - Trends in …, 2023 - cell.com
Specific RNA sequences modified by a methylated adenosine, N 6-methyladenosine (m 6
A), contribute to the post-transcriptional regulation of gene expression. The quantity of m 6 A …

m6A readers, writers, erasers, and the m6A epitranscriptome in breast cancer

BJ Petri, CM Klinge - Journal of molecular endocrinology, 2023 - jme.bioscientifica.com
Epitranscriptomic modification of RNA regulates human development, health, and disease.
The true diversity of the transcriptome in breast cancer including chemical modification of …

Zinc in cognitive impairment and aging

R Sun, J Wang, J Feng, B Cao - Biomolecules, 2022 - mdpi.com
Zinc, an essential micronutrient for life, was first discovered in 1869 and later found to be
indispensable for the normal development of plants and for the normal growth of rats and …

RNA m6A methylation in cancer

Z Wang, J Zhou, H Zhang, L Ge, J Li… - Molecular …, 2023 - Wiley Online Library
N 6‐methyladenosine (m6A) is one of the most abundant internal modifications in eukaryotic
messenger RNAs (mRNAs) and non‐coding RNAs (ncRNAs). It is a reversible and dynamic …

m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial–mesenchymal transition of lung cancer cells

K Suphakhong, M Terashima, S Wanna-Udom… - Journal of Biological …, 2022 - ASBMB
N6-methyladenosine (m6A) is the most common internal chemical modification of mRNAs
involved in many pathological processes including various cancers. In this study, we …

[HTML][HTML] Decoding m6A mRNA methylation by reader proteins in liver diseases

L Sun, X Chen, S Zhu, J Wang, S Diao, J Liu, J Xu, X Li… - Genes & …, 2024 - Elsevier
Abstract N6-methyladenosine (m 6 A) is a dynamic and reversible epigenetic regulation. As
the most prevalent internal post-transcriptional modification in eukaryotic RNA, it participates …

RNA m6A reader IGF2BP3 promotes metastasis of triple‐negative breast cancer via SLIT2 repression

T Jiang, X He, Z Zhao, X Zhang, T Wang… - The FASEB …, 2022 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is a group of fatal malignancies characterized by high
metastatic capacity, the underlying mechanisms of which remain largely elusive. We have …

Cancer metastasis under the magnifying glass of epigenetics and epitranscriptomics

M Janin, V Davalos, M Esteller - Cancer and Metastasis Reviews, 2023 - Springer
Most of the cancer-associated mortality and morbidity can be attributed to metastasis. The
role of epigenetic and epitranscriptomic alterations in cancer origin and progression has …