Cervical cancer markers: epigenetics and microRNAs

V Laengsri, U Kerdpin, C Plabplueng… - Laboratory …, 2018 - academic.oup.com
Gynecologic malignant neoplasms are a severe health problem among female patients, of
which cervical cancer (CC), in particular, is a common disease leading to high mortality …

Autotaxin in breast cancer: role, epigenetic regulation and clinical implications

A Drosouni, M Panagopoulou, V Aidinis, E Chatzaki - Cancers, 2022 - mdpi.com
Simple Summary Autotaxin (ATX) has been linked with the pathogenesis of several cancers
and especially with breast cancer (BC). BC is one of the most common cancers among …

Deciphering the methylation landscape in breast cancer: diagnostic and prognostic biosignatures through automated machine learning

M Panagopoulou, M Karaglani, VG Manolopoulos… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer (BrCa) is characterized by aberrant DNA methylation. We
leveraged high-throughput methylation data from BrCa and normal breast tissues and …

ENPP2 Promoter Methylation Correlates with Decreased Gene Expression in Breast Cancer: Implementation as a Liquid Biopsy Biomarker

M Panagopoulou, A Drosouni, D Fanidis… - International journal of …, 2022 - mdpi.com
Autotaxin (ATX), encoded by the ctonucleotide pyrophosphatase/phosphodiesterase 2
(ENPP2) gene, is a key enzyme in lysophosphatidic acid (LPA) synthesis. We have recently …

Circulating cell-free DNA in breast cancer: Searching for hidden information towards precision medicine

M Panagopoulou, M Esteller, E Chatzaki - Cancers, 2021 - mdpi.com
Simple Summary Our research focuses in the elucidation of the nature of circulating cell-free
DNA (ccfDNA) as a biological entity and its exploitation as a liquid biopsy biomaterial …

ENPP2 Methylation in Health and Cancer

M Panagopoulou, D Fanidis, V Aidinis… - International Journal of …, 2021 - mdpi.com
Autotaxin (ATX) encoded by Ectonucleotide Pyrophosphatase/Phosphodiesterase 2
(ENPP2) is a key enzyme in Lysophosphatidic Acid (LPA) synthesis implicated in cancer …

BRMS1: a multifunctional signaling molecule in metastasis

RC Zimmermann, DR Welch - Cancer and Metastasis Reviews, 2020 - Springer
Despite high mortality rates, molecular understanding of metastasis remains limited. It can
be regulated by both pro-and anti-metastasis genes. The metastasis suppressor, breast …

An epigenomic landscape of cervical intraepithelial neoplasia and cervical cancer using single‐base resolution methylome and hydroxymethylome

Y Han, L Ji, Y Guan, M Ma, P Li, Y Xue… - Clinical and …, 2021 - Wiley Online Library
Background Cervical cancer (CC) is the second leading cause of cancer death among
women worldwide. Epigenetic regulation of gene expression through DNA methylation and …

Methylation status of corticotropin-releasing factor (CRF) receptor genes in colorectal cancer

M Panagopoulou, A Cheretaki, M Karaglani… - Journal of Clinical …, 2021 - mdpi.com
The corticotropin-releasing factor (CRF) system has been strongly associated with
gastrointestinal pathophysiology, including colorectal cancer (CRC). We previously showed …

Epigenetics mechanisms mediate the miR-125a/BRMS1 axis to regulate invasion and metastasis in gastric cancer

J Xiong, Y Tu, Z Feng, D Li, Z Yang… - OncoTargets and …, 2019 - Taylor & Francis
Purpose Altered expression of breast cancer metastasis suppressor 1 (BRMS1), is a tumor
suppressor, which is found in many types of cancers, including gastric cancer (GC), but the …