Amyotrophic lateral sclerosis (ALS) is the most common motor neuron degenerative disease
in adults and has also been proven to be a type of conformational disease associated with …

Background During the last two decades, over 100 proteomics studies have identified a
variety of potential biomarkers in CSF of Alzheimer's (AD) patients. Although several reviews …

Amyotrophic lateral sclerosis (ALS) is a progressive adult-onset neurodegenerative disease,
that affects cortical, bulbar and spinal motor neurons, and it is considered a proteinopathy, in …

More than 20 distinct gene loci have so far been implicated in amyotrophic lateral sclerosis
(ALS), a fatal neurodegenerative disorder characterized by progressive neurodegeneration …

An 8-week feeding trial was conducted to evaluate effects of dietary organic zinc (zinc amino
acid chelate) on growth performance, mineral bioaccumulation in whole body …

Many chaperones favour binding to hydrophobic sequences that are flanked by basic
residues while disfavouring acidic residues. However, the origin of this bias in protein quality …

Accumulative evidence has shown the adverse effects of a geomagnetic field shielded
condition, so called a hypomagnetic field (HMF), on the metabolic processes and oxidative …

The developing nervous system is highly vulnerable to environmental toxicants especially
pesticides. Glyphosate pesticide induces neurotoxicity both in humans and rodents, but so …

Insoluble protein aggregates with fibrillar morphology called amyloids and β-barrel proteins
both share a β-sheet-rich structure. Correctly folded β-barrel proteins can not only function in …

Superoxide dismutase (SOD) and Catalase (CAT) play a crucial role as the first line of
defense antioxidant enzymes in a living cell. These enzymes neutralize the superoxide …