[HTML][HTML] Machine perfusion of donor livers for transplantation: a proposal for standardized nomenclature and reporting guidelines

SA Karangwa, P Dutkowski, P Fontes, PJ Friend… - American journal of …, 2016 - Elsevier
With increasing demand for donor organs for transplantation, machine perfusion (MP)
promises to be a beneficial alternative preservation method for donor livers, particularly …

Inflammation and oxidative stress in the context of extracorporeal cardiac and pulmonary support

S Hatami, J Hefler, DH Freed - Frontiers in immunology, 2022 - frontiersin.org
Extracorporeal circulation (ECC) systems, including cardiopulmonary bypass, and
extracorporeal membrane oxygenation have been an irreplaceable part of the …

A machine-learning approach to human ex vivo lung perfusion predicts transplantation outcomes and promotes organ utilization

AT Sage, LL Donahoe, AA Shamandy… - Nature …, 2023 - nature.com
Ex vivo lung perfusion (EVLP) is a data-intensive platform used for the assessment of
isolated lungs outside the body for transplantation; however, the integration of artificial …

Hypothermic oxygenated liver perfusion (HOPE) prevents tumor recurrence in liver transplantation from donation after circulatory death

M Mueller, M Kalisvaart, OR Joanne, S Shetty… - Annals of …, 2020 - journals.lww.com
Objective: The aim of this study was to investigate tumor recurrence after liver
transplantation for hepatocellular carcinoma (HCC), with and without hypothermic …

Primary graft dysfunction (PGD) following lung transplantation

RJ Shah, JM Diamond - Seminars in respiratory and critical …, 2018 - thieme-connect.com
Primary graft dysfunction (PGD) is a form of acute lung injury that results from ischemia
reperfusion injury (IRI) and is the major cause of early posttransplant morbidity and mortality …

[HTML][HTML] Mitochondrial transplant after ischemia reperfusion promotes cellular salvage and improves lung function during ex-vivo lung perfusion

CM Cloer, CS Givens, LK Buie, LK Rochelle… - The Journal of Heart and …, 2023 - Elsevier
Background In lung transplantation, ischemia-reperfusion injury associated with
mitochondrial damage can lead to graft rejection. Intact, exogenous mitochondria provide a …

[HTML][HTML] Machine perfusion strategies in liver transplantation

A Schlegel, X Muller, P Dutkowski - Hepatobiliary surgery and …, 2019 - ncbi.nlm.nih.gov
Abstract Machine perfusion is a hot topic in liver transplantation and several new perfusion
concepts are currently developed. Prior to introduction into routine clinical practice, however …

[HTML][HTML] Machine perfusion of thoracic organs

D Van Raemdonck, F Rega, S Rex… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
This article summarizes recent knowledge and clinical advances in machine perfusion (MP)
of thoracic organs. MP of thoracic organs has gained much attention during the last decade …

Primary graft dysfunction in lung transplantation: a review of mechanisms and future applications

L Chacon-Alberty, R Fernandez, P Jindra, M King… - …, 2023 - journals.lww.com
Lung allograft recipients have worse survival than all other solid organ transplant recipients,
largely because of primary graft dysfunction (PGD), a major form of acute lung injury …

Ex vivo lung perfusion for donor lung assessment and repair: a review of translational interspecies models

A Wang, A Ali, S Keshavjee, M Liu… - American Journal of …, 2020 - journals.physiology.org
For patients with end-stage lung disease, lung transplantation is a lifesaving therapy.
Currently however, the number of patients who require a transplant exceeds the number of …