The tumor necrosis factor receptor (TNF-R)-associated factor (TRAF) family of intracellular
proteins were originally identified as signaling adaptors that bind directly to the cytoplasmic …

Simple Summary Tumor necrosis factor (TNF) receptor associated factor-2 (TRAF2) is an
intracellular adapter protein with E3 ligase activity, which interacts with a plethora of other …

The transformation of chronic lymphocytic leukemia (CLL) to high-grade B-cell lymphoma is
known as Richter syndrome (RS), a rare event with dismal prognosis. In this study, we …

The tumor necrosis factor receptor (TNF-R)-associated factor (TRAF) family of cytoplasmic
adaptor proteins regulate the signal transduction pathways of a variety of receptors …

Autophagy is a conserved catabolic process that maintains cellular homeostasis. Autophagy
supports lung tumorigenesis and is a potential therapeutic target in lung cancer. A better …

Tumor necrosis factor receptor (TNFR)‐associated factors (TRAF s) form a family of proteins
that are best known as signaling adapters of TNFR s. However, emerging evidence …

Summary Hodgkin and Reed/Sternberg (HRS) cells in classical H odgkin lymphoma (cHL)
show constitutive activation of nuclear factor (NF)‐κB. Several genetic lesions contribute to …

The adaptor protein TNF receptor-associated factor 3 (TRAF3) serves as a powerful
negative regulator in multiple aspects of B cell biology. Early in vitro studies in transformed …

Diffuse large B cell lymphoma (DLBCL) is a complex disease comprising diverse subtypes
and genetic profiles. Possibly because of the prevalence of genetic alterations activating …

Myeloid cells, including granulocytes, monocytes, macrophages, and dendritic cells, are
crucial players in innate immunity and inflammation. These cells constitutively or inducibly …