Financial Disclosure Prof. Menon has stock ownership and has received research funding
from Abcodia Ltd, a UCL spinout company with an interest in biomarkers and commercial …

Simple Summary Ovarian cancer is a highly lethal female malignancy with high rates of
advanced stage and recurrent disease. Ovarian cancer is characterized as poorly …

PURPOSE After risk-reducing salpingo-oophorectomy (RRSO), BRCA1/2 pathogenic variant
(PV) carriers have a residual risk to develop peritoneal carcinomatosis (PC). The etiology of …

Most ovarian carcinomas are high-grade serous carcinomas (HGSC) that contain TP53
mutations, present at advanced stage, and eventually become resistant to chemotherapy …

Besides BRCA1 and BRCA2, several other inheritable mutations have been identified that
increase ovarian cancer risk. Surgical excision of the fallopian tubes and ovaries reduces …

Objective To report the frequency and features of occult carcinomas and the incidence of
subsequent cancers following risk-reducing salpingo-oophorectomy (RRSO) in BRCA …

Background Serous tubal intraepithelial carcinomas (STIC s) have been documented in high‐
grade serous ovarian carcinomas (HGSOC s). However, the rate of association between …

Ovarian cancer is the most fatal gynecologic malignancy (50% 5‐year survival) due to a
typically advanced stage at diagnosis and a high rate of recurrence. Chemoprevention …

Ovarian cancer is the leading cause of gynecologic cancer death in the world, and its
prevention and early diagnosis remain the key to its treatment, especially for high‐grade …

Serous tubal intra‐epithelial carcinoma (STIC) is the earliest morphologically recognisable
step in the development of invasive high‐grade serous carcinoma of the fallopian tube …