Logical modeling and dynamical analysis of cellular networks

W Abou-Jaoudé, P Traynard, PT Monteiro… - Frontiers in …, 2016 - frontiersin.org
The logical (or logic) formalism is increasingly used to model regulatory and signaling
networks. Complementing these applications, several groups contributed various methods …

Model checking to assess T-helper cell plasticity

W Abou-Jaoudé, PT Monteiro, A Naldi… - … in bioengineering and …, 2015 - frontiersin.org
Computational modeling constitutes a crucial step toward the functional understanding of
complex cellular networks. In particular, logical modeling has proven suitable for the …

Verifiable biology

S Konur, M Gheorghe… - Journal of the Royal …, 2023 - royalsocietypublishing.org
The formalization of biological systems using computational modelling approaches as an
alternative to mathematical-based methods has recently received much interest because …

Model-checking ecological state-transition graphs

C Thomas, M Cosme, C Gaucherel… - PLoS Computational …, 2022 - journals.plos.org
Model-checking is a methodology developed in computer science to automatically assess
the dynamics of discrete systems, by checking if a system modelled as a state-transition …

PRISM-PSY: precise GPU-accelerated parameter synthesis for stochastic systems

M Češka, P Pilař, N Paoletti, L Brim… - … Conference on Tools …, 2016 - Springer
In this paper we present PRISM-PSY, a novel tool that performs precise GPU-accelerated
parameter synthesis for continuous-time Markov chains and time-bounded temporal logic …

Parameter synthesis by parallel coloured CTL model checking

L Brim, M Češka, M Demko, S Pastva… - … Computational Methods in …, 2015 - Springer
We propose a new distributed-memory parallel algorithm for parameter synthesis from CTL
hypotheses. The algorithm colours the state space transitions by different parameterisations …

Statistical model checking for biological applications

P Zuliani - International Journal on Software Tools for Technology …, 2015 - Springer
In this paper, we survey recent work on the use of statistical model checking techniques for
biological applications. We begin with an overview of the basic modelling techniques for …

Artificial intelligence and bioinformatics

J Nicolas - A Guided Tour of Artificial Intelligence Research …, 2020 - Springer
The chapter shines a light on the strong links shared by Artificial intelligence and
Bioinformatics since many years. Bioinformatics offers many NP-hard problems that are …

Imprecise probabilistic model checking for stochastic multi-agent systems

A Termine, A Antonucci, G Primiero, A Facchini - SN Computer Science, 2023 - Springer
Standard techniques for model checking stochastic multi-agent systems usually assume the
transition probabilities describing the system dynamics to be stationary and completely …

A novel method to verify multilevel computational models of biological systems using multiscale spatio-temporal meta model checking

O Pârvu, D Gilbert - PloS one, 2016 - journals.plos.org
Insights gained from multilevel computational models of biological systems can be
translated into real-life applications only if the model correctness has been verified first. One …