Childhood to adulthood: Accounting for age dependence in healthy‐reference distributions in 129Xe gas‐exchange MRI

JW Plummer, MM Willmering… - Magnetic resonance …, 2023 - Wiley Online Library
Purpose Xenon‐129 (129Xe) gas‐exchange MRI is a pulmonary‐imaging technique that
provides quantitative metrics for lung structure and function and is often compared to …

Hyperpolarized gas imaging in lung diseases: functional and artificial intelligence perspective

Z Zhang, H Li, S Xiao, Q Zhou, S Liu, X Zhou, L Fan - Academic Radiology, 2024 - Elsevier
Pathophysiologic changes in lung diseases are often accompanied by changes in
ventilation and gas exchange. Comprehensive evaluation of lung function cannot be …

Targeted Imaging of Lung Cancer with Hyperpolarized 129Xe MRI Using Surface-Modified Iron Oxide Nanoparticles as Molecular Contrast Agents

A Kimura, S Utsumi, A Shimokawa, R Nishimori… - Cancers, 2022 - mdpi.com
Simple Summary Hyperpolarized 129Xe (HP 129Xe) MRI was used to demonstrate the
feasibility of targeted imaging of lung cancer using two cancer-specific surface-modified iron …

Lung Volume Dependence and Repeatability of Hyperpolarized 129Xe MRI Gas Uptake Metrics in Healthy Volunteers and Participants with …

WJ Garrison, K Qing, M He, L Zhao… - Radiology …, 2023 - pubs.rsna.org
Purpose To assess the effect of lung volume on measured values and repeatability of xenon
129 (129Xe) gas uptake metrics in healthy volunteers and participants with chronic …

Effect of indacaterol/glycopyrronium on ventilation and perfusion in COPD: a randomized trial

D Singh, JM Wild, D Saralaya, R Lawson… - Respiratory …, 2022 - Springer
Rationale The long-acting β2-agonist/long-acting muscarinic antagonist combination
indacaterol/glycopyrronium (IND/GLY) elicits bronchodilation, improves symptoms, and …

Association of moderate-to-vigorous physical activity with reduction of acute exacerbation in COPD patients using a dual ultra-long-acting bronchodilators

T Kim, H Kim, SH Shin, Y Im, S Kong, HS Choi, S Zo… - Scientific Reports, 2024 - nature.com
Inhaler therapy and physical activity (PA) are important methods of chronic obstructive
pulmonary disease (COPD) management. This study aimed to investigate the additional …

Functional imaging in asthma and COPD: design of the NOVELTY ADPro substudy

H Marshall, JM Wild, LJ Smith, L Hardaker… - ERJ Open …, 2023 - Eur Respiratory Soc
The NOVEL observational longiTudinal studY (NOVELTY; ClinicalTrials. gov identifier
NCT02760329) is a global, prospective, observational study of∼ 12 000 patients with a …

Investigating the impact of RF saturation‐pulse parameters on compartment‐selective gas‐phase depolarization with xenon polarization transfer contrast MRI

T Achekzai, K Ruppert, L Loza… - Magnetic resonance …, 2022 - Wiley Online Library
Purpose To demonstrate the utility of continuous‐wave (CW) saturation pulses in xenon‐
polarization transfer contrast (XTC) MRI and MRS, to investigate the selectivity of CW pulses …

MR Imaging for the Evaluation of Diffuse Lung Disease: Where Are We?

B O'Sullivan-Murphy, B Driehuys… - Radiologic …, 2022 - radiologic.theclinics.com
Diffuse lung disease represents an umbrella term comprising a collection of lung disorders.
Clinical assessment of patients requires thorough medical and social history and physical …

Functional gas exchange measures on 129Xe MRI and spectroscopy are associated with age, sex, and BMI in healthy subjects

D Mummy, S Zhang, A Bechtel, J Lu… - Frontiers in …, 2024 - frontiersin.org
Introduction Hyperpolarized 129Xe MRI and spectroscopy is a rapidly growing technique for
assessing lung function, with applications in a wide range of obstructive, restrictive, and …