[HTML][HTML] Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review
C Neunert, N Noroozi, G Norman, GR Buchanan… - Journal of Thrombosis …, 2015 - Elsevier
Background The burden of severe bleeding in adults and children with immune
thrombocytopenia (ITP) has not been established. Objectives To describe the frequency and …
thrombocytopenia (ITP) has not been established. Objectives To describe the frequency and …
Is fresh frozen plasma clinically effective? A systematic review of randomized controlled trials
SJ Stanworth, SJ Brunskill, CJ Hyde… - British journal of …, 2004 - Wiley Online Library
Randomized controlled trials of good quality are a recognized means to robustly assess the
efficacy of interventions in clinical practice. A systematic identification and appraisal of all …
efficacy of interventions in clinical practice. A systematic identification and appraisal of all …
Dose of prophylactic platelet transfusions and prevention of hemorrhage
SJ Slichter, RM Kaufman, SF Assmann… - … England Journal of …, 2010 - Mass Medical Soc
Background We conducted a trial of prophylactic platelet transfusions to evaluate the effect
of platelet dose on bleeding in patients with hypoproliferative thrombocytopenia. Methods …
of platelet dose on bleeding in patients with hypoproliferative thrombocytopenia. Methods …
Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia
NH Afdhal, EG Giannini, G Tayyab… - … England Journal of …, 2012 - Mass Medical Soc
Background Eltrombopag is an oral thrombopoietin-receptor agonist. This study evaluated
the efficacy of eltrombopag for increasing platelet counts and reducing the need for platelet …
the efficacy of eltrombopag for increasing platelet counts and reducing the need for platelet …
Results of a randomized, double‐blind study of romiplostim versus placebo in patients with low/intermediate‐1–risk myelodysplastic syndrome and thrombocytopenia
A Giagounidis, GJ Mufti, P Fenaux, MA Sekeres… - Cancer, 2014 - Wiley Online Library
BACKGROUND Thrombocytopenia in patients with myelodysplastic syndrome (MDS) is
associated with shortened survival and an increased risk of evolution to acute myeloid …
associated with shortened survival and an increased risk of evolution to acute myeloid …
Prospective, observational study of outcomes in neonates with severe thrombocytopenia
SJ Stanworth, P Clarke, T Watts, S Ballard, L Choo… - …, 2009 - publications.aap.org
OBJECTIVE: A cross-sectional, observational study of outcomes for neonates with severe
neonatal thrombocytopenia (SNT; platelet count of< 60× 109 platelets per L) was performed …
neonatal thrombocytopenia (SNT; platelet count of< 60× 109 platelets per L) was performed …
Long-term follow-up for up to 5 years on the risk of leukaemic progression in thrombocytopenic patients with lower-risk myelodysplastic syndromes treated with …
HM Kantarjian, P Fenaux, MA Sekeres, J Szer… - The Lancet …, 2018 - thelancet.com
Background Treatment options for thrombocytopenia in myelodysplastic syndromes are
scarce. As described previously in a randomised phase 2 study (n= 250), 58 weeks of …
scarce. As described previously in a randomised phase 2 study (n= 250), 58 weeks of …
How I use platelet transfusions
SJ Stanworth, A Shah - Blood, The Journal of the American …, 2022 - ashpublications.org
Platelet transfusions are commonly administered for the prevention or treatment of bleeding
in patients with acquired thrombocytopenia across a range of clinical contexts. Recent data …
in patients with acquired thrombocytopenia across a range of clinical contexts. Recent data …
Prophylactic platelet transfusion for prevention of bleeding in patients with haematological disorders after chemotherapy and stem cell transplantation
L Estcourt, S Stanworth, C Doree… - Cochrane Database …, 2012 - cochranelibrary.com
Background Platelet transfusions are used in modern clinical practice to prevent and treat
bleeding in thrombocytopenic patients with bone marrow failure. Although considerable …
bleeding in thrombocytopenic patients with bone marrow failure. Although considerable …
Optimal preprocedural platelet transfusion threshold for central venous catheter insertions in patients with thrombocytopenia
K Zeidler, K Arn, O Senn, U Schanz, G Stussi - Transfusion, 2011 - Wiley Online Library
BACKGROUND: Patients with severe thrombocytopenia are at risk for bleeding during
insertion of central venous catheters (CVCs). Although most guidelines recommend …
insertion of central venous catheters (CVCs). Although most guidelines recommend …