The horse reference genome from the Thoroughbred mare Twilight has been available for a
decade and, together with advances in genomics technologies, has led to unparalleled …

Using analytical chemistry techniques such as nuclear magnetic resonance (NMR)
spectroscopy and liquid or gas chromatography–mass spectrometry (LC/GC-MS) …

Field tests and their association with laminitis have not been evaluated in large cohorts. The
objectives of this study were to evaluate the performance of basal insulin (BI), the oral sugar …

Simple Summary Antimicrobials reduced the diversity and altered the bacterial community
composition of the fecal microbiome of horses. Horses that develop antimicrobial-associated …

Metabolic diseases such as obesity and type 2 diabetes in humans have been linked to
alterations in the gastrointestinal microbiota and metabolome. Knowledge of these …

Background Little is known about the implications of hyperinsulinemia on energy
metabolism, and such knowledge might help understand the pathophysiology of insulin …

Bovine laminitis disorder results in animal welfare and economic concerns in dairy and beef
farms worldwide. However, the affected metabolic pathways, pathophysiologic …

The objective of this study was to investigate the effect of essential oil (EO) supplementation
on insulin sensitivity (IS) and the plasma metabolome in insulin dysregulated (ID) horses …

Background Insulin dysregulation (ID) is a key risk factor for equine endocrinopathic
laminitis, but in many cases ID can only be assessed accurately using dynamic tests. The …

Endocrinopathies affect multiple species in ever-increasing percentages of their
populations, creating an opportunity to apply one-health approaches to determining creative …