Background The molecular and cellular mechanisms underlying the pathogenesis of oral
squamous cell carcinoma (OSCC) are relatively poorly understood and remain a subject of …

Major technological advances have made proteomics an extremely active field for biomarker
discovery and validation in recent years. These improvements have lead to an increased …

Acquired platinum resistance poses a significant therapeutic impediment to ovarian cancer
patient care, accounting for more than 200,000 deaths annually worldwide. We previously …

Background Following amputation, urodele salamander limbs reprogram somatic cells to
form a blastema that self-organizes into the missing limb parts to restore the structure and …

Background: Carboplatin and paclitaxel form the cornerstone of chemotherapy for epithelial
ovarian cancer, however, drug resistance to these agents continues to present challenges …

Anticancer metallodrug development has for a long time been characterised by the similarity
of new drug candidates to cisplatin and DNA as the primary target. Recent advances in …

A number of studies have reported aberrant glycosylation in connection with malignancy.
Our investigation further expands on this topic through the examination of N-glycans, which …

Background Melanoma metastasis status is highly associated with the overall survival of
patients; yet, little is known about proteomic changes during melanoma tumor progression …

Purpose Clinical drug resistance to platinum-based chemotherapy is considered a major
impediment in the treatment of human ovarian cancer. Multiple pathways associated with …

Background To gain insight into what differences might restrict the capacity for limb
regeneration in Xenopus froglets, we used High Performance Liquid Chromatography …