Bridging the gap: Prenatal nutrition, myelination, and schizophrenia etiopathogenesis

M Ortiz-Valladares, O Gonzalez-Perez… - Neuroscience, 2024 - Elsevier
Schizophrenia (SZ) is a complex mental illness characterized by disturbances in thinking,
emotionality, and behavior, significantly impacting the quality of life for individuals affected …

[HTML][HTML] HIV-1 Tat-mediated microglial ferroptosis involves the miR-204–ACSL4 signaling axis

M Kannan, S Sil, A Oladapo, A Thangaraj… - Redox Biology, 2023 - Elsevier
This study was focused on exploring the role of the HIV-1 Tat protein in mediating microglial
ferroptosis. Exposure of mouse primary microglial cells (mPMs) to HIV-1 Tat protein resulted …

Insights on therapeutic potential of clemastine in neurological disorders

S Jiang, X Wang, T Cao, R Kang… - Frontiers in Molecular …, 2023 - frontiersin.org
Clemastine, a Food and Drug Administration (FDA)-approved compound, is recognized as a
first-generation, widely available antihistamine that reduces histamine-induced symptoms …

[HTML][HTML] Maternal Docosahexaenoic Acid Supplementation Alters Maternal and Fetal Docosahexaenoic Acid Status and Placenta Phospholipids in Pregnancies …

KL Bidne, K Zemski Berry, M Dillon, T Jansson… - Nutrients, 2024 - mdpi.com
Introduction: An optimal fetal supply of docosahexaenoic acid (DHA) is critical for normal
brain development. The relationship between maternal DHA intake and DHA delivery to the …

Modified neuroimmune processes and emotional behaviour in weaned and late adolescent male and female mice born via caesarean section

MD Miceli, M Rossitto, M Martinat, F Marchaland… - Scientific Reports, 2024 - nature.com
Elective and emergency Caesarean section (C-section) procedures are on the rise,
exceeding the recommended guidelines by the World Health Organization. Higher …

Beyond ingredients: Supramolecular structure of lipid droplets in infant formula affects metabolic and brain function in mouse models

A Oosting, L Harvey, S Ringler, G van Dijk… - PLoS One, 2023 - journals.plos.org
Human milk beneficially affects infant growth and brain development. The supramolecular
structure of lipid globules in human milk ie, large lipid globules covered by the milk fat …

Maternal n-3 enriched diet reprograms the offspring neurovascular transcriptome and blunts inflammation induced by endotoxin in the neonate

T Chumak, A Jullienne, CJ Ek, M Ardalan… - Journal of …, 2024 - Springer
Infection during the perinatal period can adversely affect brain development, predispose
infants to ischemic stroke and have lifelong consequences. We previously demonstrated that …

N-3 PUFA deficiency affects the ultrastructural organization and density of white matter microglia in the developing brain of male mice

F Decoeur, K Picard, MK St-Pierre… - Frontiers in Cellular …, 2022 - frontiersin.org
Over the last century, westernization of dietary habits has led to a dramatic reduction in
dietary intake of n-3 polyunsaturated fatty acids (n-3 PUFAs). In particular, low maternal …

Lipid analysis of breast milk and formula for preterm infants and the application and prospects of novel structural lipids–a comprehensive review

N Wang, M Ma, G Mu, F Qian… - Critical Reviews in Food …, 2024 - Taylor & Francis
Preterm infants, often characterized by lower birth weights and underdeveloped
physiologies, necessitate specialized nutritional care. While breast milk stands as the ideal …

[HTML][HTML] Counteracting the effects of maternal obesity on offspring neurodevelopment through Omega-3-based nutritional strategies

M Samà, C Musillo, F Cirulli - Neuroscience, 2025 - Elsevier
It is becoming increasingly recognized that, in addition to psychological stress, unbalanced
maternal nutritional habits can threaten fetal brain development. Maternal obesity is one of …