COVID‐19 and plasma cells: Is there long‐lived protection?

DC Nguyen, PA Lamothe, MC Woodruff… - Immunological …, 2022 - Wiley Online Library
Summary Infection with SARS‐CoV‐2, the etiology of the ongoing COVID‐19 pandemic, has
resulted in over 450 million cases with more than 6 million deaths worldwide, causing global …

Immune mechanisms associated with sex-based differences in severe COVID-19 clinical outcomes

CG Arnold, A Libby, A Vest, A Hopkinson… - Biology of sex …, 2022 - Springer
Background Although biological males and females are equally likely to become infected
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), evidence has …

A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus

WA Fischer, JJ Eron Jr, W Holman, MS Cohen… - Science translational …, 2021 - science.org
There is an urgent need for an effective, oral, direct-acting therapeutic to block transmission
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …

Molnupiravir, an oral antiviral treatment for COVID-19

W Fischer, JJ Eron Jr, W Holman, MS Cohen, L Fang… - MedRxiv, 2021 - medrxiv.org
Background Easily distributed oral antivirals are urgently needed to treat coronavirus
disease-2019 (COVID-19), prevent progression to severe illness, and block transmission of …

SARS-CoV-2 antibody kinetics eight months from COVID-19 onset: Persistence of spike antibodies but loss of neutralizing antibodies in 24% of convalescent plasma …

E Terpos, D Stellas, M Rosati, TN Sergentanis… - European journal of …, 2021 - Elsevier
Elucidating the characteristics of human immune response against SARS-CoV-2 is of high
priority and relevant for determining vaccine strategies. We report the results of a follow-up …

[HTML][HTML] Protective immunity after natural infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)–Kentucky, USA, 2020

KB Spicer, C Glick, AM Cavanaugh… - International Journal of …, 2022 - Elsevier
Background As vaccine supply and access remain limited in many parts of the world,
understanding the duration of protection from reinfection after natural infection is important …

Sequential analysis of binding and neutralizing antibody in COVID-19 convalescent patients at 14 months after SARS-CoV-2 infection

M Rosati, E Terpos, I Ntanasis-Stathopoulos… - Frontiers in …, 2021 - frontiersin.org
Durability of SARS-CoV-2 Spike antibody responses after infection provides information
relevant to understanding protection against COVID-19 in humans. We report the results of a …

Durability and breadth of neutralisation following multiple antigen exposures to SARS-CoV-2 infection and/or COVID-19 vaccination

AP Underwood, C Sølund, C Fernandez-Antunez… - …, 2023 - thelancet.com
Background Given the importance of vaccination against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) in the prevention of severe coronavirus disease 2019 (COVID …

Anti-spike and neutralizing antibodies after two doses of COVID-19 sinopharm/BIBP vaccine

EA Omran, RE El Naggar, LA Ezz Elarab, MH Hashish… - Vaccines, 2022 - mdpi.com
Host response to COVID-19 vaccines is partially evaluated through the estimation of
antibody response, specifically the binding anti-spike (anti-S) and the neutralizing …

Applications of SARS-CoV-2 serological testing: impact of test performance, sample matrices, and patient characteristics

CYJ Fung, M Scott, J Lerner-Ellis… - Critical reviews in clinical …, 2024 - Taylor & Francis
Laboratory testing has been a key tool in managing the SARS-CoV-2 global pandemic.
While rapid antigen and PCR testing has proven useful for diagnosing acute SARS-CoV-2 …