Overview of dual-acting drug methotrexate in different neurological diseases, autoimmune pathologies and cancers

P Koźmiński, PK Halik, R Chesori… - International journal of …, 2020 - mdpi.com
Methotrexate, a structural analogue of folic acid, is one of the most effective and extensively
used drugs for treating many kinds of cancer or severe and resistant forms of autoimmune …

Nano carriers for drug transport across the blood–brain barrier

X Li, J Tsibouklis, T Weng, B Zhang, G Yin… - Journal of drug …, 2017 - Taylor & Francis
Effective therapy lies in achieving a therapeutic amount of drug to the proper site in the body
and then maintaining the desired drug concentration for a sufficient time interval to be …

Plant extracts: from encapsulation to application

B Armendáriz-Barragán, N Zafar, W Badri… - Expert Opinion on …, 2016 - Taylor & Francis
Introduction: Plants are a natural source of various products with diverse biological activities
offering treatment for several diseases. Plant extract is a complex mixture of compounds …

Encapsulation of NSAIDs for inflammation management: overview, progress, challenges and prospects

W Badri, K Miladi, QA Nazari, H Greige-Gerges… - International journal of …, 2016 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely prescribed
drugs. Debilitating diseases such as rheumatoid arthritis and osteoarthritis are commonly …

Molecular determinants of blood–brain barrier permeation

WJ Geldenhuys, AS Mohammad, CE Adkins… - Therapeutic …, 2015 - Taylor & Francis
The blood–brain barrier (BBB) is a microvascular unit which selectively regulates the
permeability of drugs to the brain. With the rise in CNS drug targets and diseases, there is a …

Biomedical nanoparticles: overview of their surface immune-compatibility

O Gamucci, A Bertero, M Gagliardi, G Bardi - Coatings, 2014 - mdpi.com
Diagnostic-and therapeutic release-aimed nanoparticles require the highest degree of
biocompatibility. Some physical and chemical characteristics of such nanomaterials are …

Nanotechnology-based drug delivery systems for targeting, imaging and diagnosis of neurodegenerative diseases

S Bozdağ Pehlivan - Pharmaceutical research, 2013 - Springer
Neurodegenerative disorders are becoming prevalent with the increasing age of the general
population. A number of difficulties have emerged for the potential treatment of …

Techniques in electron microscopy of animal tissue

NF Cheville, J Stasko - Veterinary pathology, 2014 - journals.sagepub.com
Technical improvements in electron microscopy, both instrumental and preparative, permit
increasingly accurate analyses. Digital images for transmission electron microscopy (TEM) …

Effect of process and formulation parameters on polycaprolactone nanoparticles prepared by solvent displacement

W Badri, K Miladi, QA Nazari, H Fessi… - Colloids and surfaces A …, 2017 - Elsevier
Solvent displacement in comparison with other polymeric particles preparation technique
provides certain crucial advantages such as water, time and energy lower consumption …

Biodegradation of medical purpose polymeric materials and their impact on biocompatibility

E Tamariz, A Rios-Ramírez - Biodegradation-Life of Science …, 2013 - books.google.com
The use of polymeric materials in medical devices and pharmaceutical applications has
been extended in the last decades. Biodegradable implantable polymers for tissue …