Deciphering miRNAs' action through miRNA editing

M Correia de Sousa, M Gjorgjieva, D Dolicka… - International journal of …, 2019 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene
expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) …

The non-canonical aspects of microRNAs: many roads to gene regulation

CJ Stavast, SJ Erkeland - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …

MicroRNA in control of gene expression: an overview of nuclear functions

C Catalanotto, C Cogoni, G Zardo - International journal of molecular …, 2016 - mdpi.com
The finding that small non-coding RNAs (ncRNAs) are able to control gene expression in a
sequence specific manner has had a massive impact on biology. Recent improvements in …

Nuclear functions of mammalian MicroRNAs in gene regulation, immunity and cancer

H Liu, C Lei, Q He, Z Pan, D Xiao, Y Tao - Molecular cancer, 2018 - Springer
MicroRNAs (miRNAs) are endogenous non-coding RNAs that contain approximately 22
nucleotides. They serve as key regulators in various biological processes and their …

Small non-coding RNA and cancer

G Romano, D Veneziano, M Acunzo… - …, 2017 - academic.oup.com
The ENCODE project has reported that at least 80% of the human genome is biologically
active, yet only a small part of human DNA encodes for protein. The massive amount of RNA …

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

MR Friedländer, SD Mackowiak, N Li… - Nucleic acids …, 2012 - academic.oup.com
Abstract microRNAs (miRNAs) are a large class of small non-coding RNAs which post-
transcriptionally regulate the expression of a large fraction of all animal genes and are …

tRNA-derived small RNA: a novel regulatory small non-coding RNA

S Li, Z Xu, J Sheng - Genes, 2018 - mdpi.com
Deep analysis of next-generation sequencing data unveils numerous small non-coding
RNAs with distinct functions. Recently, fragments derived from tRNA, named as tRNA …

Emerging functions for snoRNAs and snoRNA-derived fragments

M Wajahat, CP Bracken, A Orang - International journal of molecular …, 2021 - mdpi.com
The widespread implementation of mass sequencing has revealed a diverse landscape of
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …

MicroRNA: biogenesis, function and role in cancer

LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …

miRNA‐dependent gene silencing involving Ago2‐mediated cleavage of a circular antisense RNA

TB Hansen, ED Wiklund, JB Bramsen… - The EMBO …, 2011 - embopress.org
MicroRNAs (miRNAs) are∼ 22 nt non‐coding RNAs that typically bind to the 3′ UTR of
target mRNAs in the cytoplasm, resulting in mRNA destabilization and translational …