Vitamin K: double bonds beyond coagulation insights into differences between vitamin K1 and K2 in health and disease

M Halder, P Petsophonsakul, AC Akbulut… - International journal of …, 2019 - mdpi.com
Vitamin K is an essential bioactive compound required for optimal body function. Vitamin K
can be present in various isoforms, distinguishable by two main structures, namely …

Role of vitamin K in intestinal health

Y Lai, H Masatoshi, Y Ma, Y Guo, B Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Intestinal diseases, such as inflammatory bowel diseases (IBDs) and colorectal cancer
(CRC) generally characterized by clinical symptoms, including malabsorption, intestinal …

A novel anti-osteoporosis mechanism of VK2: interfering with ferroptosis via AMPK/SIRT1 pathway in type 2 diabetic osteoporosis

C Jin, K Tan, Z Yao, B Lin, D Zhang… - Journal of Agricultural …, 2023 - ACS Publications
Type 2 diabetic osteoporosis (T2DOP) is a chronic bone metabolic disease. Compared with
traditional menopausal osteoporosis, the long-term high glucose (HG) microenvironment …

[HTML][HTML] Emerging mechanisms and targeted therapy of ferroptosis in neurological diseases and neuro-oncology

Y Wang, B Tang, J Zhu, J Yu, J Hui… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Ferroptosis is a novel type of cell death characterized by iron-dependent lipid peroxidation
that involves a variety of biological processes, such as iron metabolism, lipid metabolism …

Molecular pathways and roles for vitamin K2-7 as a health-beneficial nutraceutical: Challenges and opportunities

N Jadhav, S Ajgaonkar, P Saha, P Gurav… - Frontiers in …, 2022 - frontiersin.org
Vitamin K2-7, also known as menaquinone-7 (MK-7) is a form of vitamin K that has health-
beneficial effects in osteoporosis, cardiovascular disease, inflammation, cancer, Alzheimer's …

The biological responses of vitamin K2: A comprehensive review

Q Yan, T Zhang, C O'Connor, JW Barlow… - Food Science & …, 2023 - Wiley Online Library
Abstract Vitamin K1 (VitK1) and Vitamin K2 (VitK2), two important naturally occurring
micronutrients in the VitK family, found, respectively, in green leafy plants and algae (VitK1) …

Relationship between structure and biological activity of various vitamin K forms

K Bus, A Szterk - Foods, 2021 - mdpi.com
Vitamin K is involved many biological processes, such as the regulation of blood
coagulation, prevention of vascular calcification, bone metabolism and modulation of cell …

Revisiting the role of vitamins and minerals in Alzheimer's disease

H Shah, F Dehghani, M Ramezan, RB Gannaban… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common type of dementia that affects millions of
individuals worldwide. It is an irreversible neurodegenerative disorder that is characterized …

Protective effect of Ginkgolide B against cognitive impairment in mice via regulation of gut microbiota

J Liu, T Ye, Y Zhang, R Zhang, Y Kong… - Journal of Agricultural …, 2021 - ACS Publications
Ginkgolide B (GB) is one of the main bioactive components of Ginkgo biloba leaf extracts
with neuroprotective activity. However, the neuroprotective mechanism link between the anti …

Non-polyphenolic natural inhibitors of amyloid aggregation

L Ma, C Yang, J Zheng, Y Chen, Y Xiao… - European journal of …, 2020 - Elsevier
Protein misfolding diseases (PMDs) are chronic and progressive, with no effective therapy
so far. Aggregation and misfolding of amyloidogenic proteins are closely associated with the …