Current developments of coumarin-based anti-cancer agents in medicinal chemistry

S Emami, S Dadashpour - European Journal of Medicinal Chemistry, 2015 - Elsevier
Cancer is one of the leading health hazards and the prominent cause of death in the world.
A number of anticancer agents are currently in clinical practice and used for treatment of …

Coumarin heterocyclic derivatives: chemical synthesis and biological activity

FG Medina, JG Marrero, M Macías-Alonso… - Natural product …, 2015 - pubs.rsc.org
Coumarin heterocyclic derivatives: chemical synthesis and biological activity - Natural Product
Reports (RSC Publishing) DOI:10.1039/C4NP00162A Royal Society of Chemistry View PDF …

A review on coumarins as acetylcholinesterase inhibitors for Alzheimer's disease

P Anand, B Singh, N Singh - Bioorganic & medicinal chemistry, 2012 - Elsevier
Acetylcholinesterase (AChE) enzyme inhibition is an important target for the management of
Alzheimer disease (AD) and AChE inhibitors are the main stay drugs for its management …

Current developments of coumarin compounds in medicinal chemistry

XM Peng, G LV Damu, H Zhou - Current pharmaceutical …, 2013 - ingentaconnect.com
Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

Recent progress in the drug development of coumarin derivatives as potent antituberculosis agents

RS Keri, BS Sasidhar, BM Nagaraja… - European journal of …, 2015 - Elsevier
Tuberculosis (TB) is still a challenging worldwide health problem and mycobacterium
tuberculosis (MTB) remains one of the most deadly human pathogens. TB is the second …

Visible-light initiated oxidative cyclization of phenyl propiolates with sulfinic acids to coumarin derivatives under metal-free conditions

W Yang, S Yang, P Li, L Wang - Chemical Communications, 2015 - pubs.rsc.org
A visible-light initiated oxidative cyclization of phenyl propiolates with sulfinic acids has been
developed. The arylsulfonylation of alkynes was performed at room temperature under metal …

Electrochemical oxidative cyclization of activated alkynes with diselenides or disulfides: access to functionalized coumarins or quinolinones

J Hua, Z Fang, J Xu, M Bian, CK Liu, W He, N Zhu… - Green …, 2019 - pubs.rsc.org
A direct electrochemical oxidative cyclization of alkynoates and alkynamides with
diselenides or disulfides for the synthesis of coumarins and quinolinones bearing a …

Recent advances and therapeutic journey of coumarins: current status and perspectives

KP Barot, SV Jain, L Kremer, S Singh… - Medicinal Chemistry …, 2015 - Springer
Coumarins are oxygen-containing molecules with specific benzopyrone nucleus. Different
coumarins are identified as antineurodegeneratives, anticoagulants, antioxidants …

[HTML][HTML] New coumarin derivative with potential antioxidant activity: Synthesis, DNA binding and in silico studies (Docking, MD, ADMET)

S Kecel-Gunduz, Y Budama-Kilinc, B Bicak… - Arabian Journal of …, 2023 - Elsevier
Abstract A new coumarin derivative, 7-((8-(4-benzylpiperidin-1-yl) octyl) oxy)-4-methyl-2H-
chromen-2-one (C3), was synthesized by two-step alkylation reaction of 7-hydroxy-4-methyl …

Recent advances in photocatalytic C–S/P–S bond formation via the generation of sulfur centered radicals and functionalization

W Guo, K Tao, W Tan, M Zhao, L Zheng… - Organic Chemistry …, 2019 - pubs.rsc.org
Thioyl and sulfonyl radicals are usually produced from various thiols and sulfonyl derivatives
in high efficiency by single-electron-transfer (SET) oxidation. The generated sulfur …