Thymoquinone and its therapeutic potentials

S Darakhshan, AB Pour, AH Colagar… - Pharmacological …, 2015 - Elsevier
Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …

[HTML][HTML] Frankincense–therapeutic properties

ARM Al-Yasiry, B Kiczorowska - Advances in Hygiene and Experimental …, 2016 - phmd.pl
Recently, increasing interest in natural dietary and therapeutic preparations used as dietary
supplements has been observed. One of them is frankincense. This traditional medicine of …

Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats

S Umar, J Zargan, K Umar, S Ahmad, CK Katiyar… - Chemico-biological …, 2012 - Elsevier
Thymoquinone (TQ) is the major active compound derived from Nigella sativa. Our aim of
this work was to evaluate the antioxidant and antiarthritic activity of TQ in Wistar rat by …

Boswellia serrata extract attenuates inflammatory mediators and oxidative stress in collagen induced arthritis

S Umar, K Umar, AHMG Sarwar, A Khan, N Ahmad… - Phytomedicine, 2014 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disease which leads to destruction of
joints. Current treatment modalities for RA either produce symptomatic relief (NSAIDs) or …

Bone-to-brain: a round trip in the adaptation to mechanical stimuli

L Gerosa, G Lombardi - Frontiers in Physiology, 2021 - frontiersin.org
Besides the classical ones (support/protection, hematopoiesis, storage for calcium, and
phosphate) multiple roles emerged for bone tissue, definitively making it an organ …

[HTML][HTML] Effects of Nigella sativa oil extract on inflammatory cytokine response and oxidative stress status in patients with rheumatoid arthritis: a randomized, double …

V Hadi, S Kheirouri, M Alizadeh… - Avicenna journal of …, 2016 - ncbi.nlm.nih.gov
Objective: Nigella sativa is a medicinal plant that has long been used in traditional medicine
for treating various conditions. Numerous animal studies provided evidences that the seed …

The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis

S Sutton, A Clutterbuck, P Harris, T Gent, S Freeman… - The veterinary …, 2009 - Elsevier
Osteoarthritis (OA) is one of the most common and disabling chronic joint disorders affecting
horses, dogs and humans. Synovial inflammation or synovitis is a frequently observed …

Bone and muscle loss after spinal cord injury: organ interactions

W Qin, WA Bauman, C Cardozo - … of the New York Academy of …, 2010 - Wiley Online Library
Spinal cord injury (SCI) results in paralysis and marked loss of skeletal muscle and bone
below the level of injury. Modest muscle activity prevents atrophy, whereas much larger …

Nanomedicine–advantages for their use in rheumatoid arthritis theranostics

S Xiao, Y Tang, Z Lv, Y Lin, L Chen - Journal of controlled release, 2019 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease accompanies with synovial
inflammation and progressive bone destruction. Currently, anti-rheumatic drugs need high …

Crosstalk of brain and bone—clinical observations and their molecular bases

E Otto, PR Knapstein, D Jahn, J Appelt… - International journal of …, 2020 - mdpi.com
As brain and bone disorders represent major health issues worldwide, substantial clinical
investigations demonstrated a bidirectional crosstalk on several levels, mechanistically …