To monitor inflammation in a meaningful way, the markers used must be valid: they must
reflect the inflammatory process under study and they must be predictive of future health …

Introduction: The advent of high throughput technologies capable of comprehensive
analysis of genes, transcripts, proteins and other significant biological molecules has …

Obesity is a significant contemporary health concern that carries wide-ranging implications
for society, as well as for individual health and well-being. In particular, the …

The complement system has been implicated in obesity, fatty liver, diabetes and
cardiovascular disease (CVD). Complement factors are produced in adipose tissue and …

Current nutritional and genetic epidemiological methods yield 'risk factors' on the basis of
population studies. Risk factors, however, are statistical estimates of the percentage …

BACKGROUND: The neurotrophic hypothesis suggests that mood disorders are associated
with dysfunction of neuronal networks under the influence of neurotrophic factors. Vascular …

Background Obesity may be associated with a range of cardiometabolic manifestations. We
hypothesized that proteomic profiling may provide insights into the biological pathways that …

Background Characterization of abdominal and intra-abdominal fat requires imaging, and
thus is not feasible in large epidemiologic studies. Objective We investigated whether …

Background Approximately 20% of obese dogs have metabolic disturbances similar to those
observed in human metabolic syndrome, a condition known as obesity-related metabolic …

Background The ability of subjects to respond to nutritional challenges can reflect the
flexibility of their biological system. Nutritional challenge tests could be used as an indicator …