[HTML][HTML] Environmental pollution, a hidden culprit for health issues

H Xu, Y Jia, Z Sun, J Su, QS Liu, Q Zhou… - Eco-Environment & …, 2022 - Elsevier
The environmental and health impacts from the massive discharge of chemicals and
subsequent pollution have been gaining increasing public concern. The unintended …

Polychlorinated biphenyls (PCBs) in the environment: occupational and exposure events, effects on human health and fertility

L Montano, C Pironti, G Pinto, M Ricciardi, A Buono… - Toxics, 2022 - mdpi.com
In the last decade or so, polychlorinated biphenyls (PCBs) garnered renewed attention in
the scientific community due to new evidence pointing at their continued presence in the …

Consensus paper: pathological role of the cerebellum in autism

SH Fatemi, KA Aldinger, P Ashwood, ML Bauman… - The Cerebellum, 2012 - Springer
There has been significant advancement in various aspects of scientific knowledge
concerning the role of cerebellum in the etiopathogenesis of autism. In the current …

Early environmental risk factors for neurodevelopmental disorders–a systematic review of twin and sibling studies

T Carlsson, F Molander, MJ Taylor… - Development and …, 2021 - cambridge.org
While neurodevelopmental disorders (NDDs) are highly heritable, several environmental
risk factors have also been suggested. However, the role of familial confounding is unclear …

Neurotoxicity of polychlorinated biphenyls and related organohalogens

IN Pessah, PJ Lein, RF Seegal, SK Sagiv - Acta neuropathologica, 2019 - Springer
Halogenated organic compounds are pervasive in natural and built environments. Despite
restrictions on the production of many of these compounds in most parts of the world through …

Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment

PE Goines, P Ashwood - Neurotoxicology and teratology, 2013 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental diseases that affect an alarming
number of individuals. The etiological basis of ASD is unclear, and evidence suggests it …

A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity

LG Costa, R de Laat, S Tagliaferri, C Pellacani - Toxicology letters, 2014 - Elsevier
Polybrominated diphenyl ethers (PBDEs), extensively used in the past few decades as flame
retardants in a variety of consumer products, have become world-wide persistent …

Evidence implicating non-dioxin-like congeners as the key mediators of polychlorinated biphenyl (PCB) developmental neurotoxicity

C Klocke, PJ Lein - International journal of molecular sciences, 2020 - mdpi.com
Despite being banned from production for decades, polychlorinated biphenyls (PCBs)
continue to pose a significant risk to human health. This is due to not only the continued …

Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure

BI Laufer, K Neier, AE Valenzuela, DH Yasui… - Cell reports, 2022 - cell.com
Polychlorinated biphenyls (PCBs) are developmental neurotoxicants implicated as
environmental risk factors for neurodevelopmental disorders (NDDs). Here, we report the …

DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders?

KP Keil, PJ Lein - Environmental epigenetics, 2016 - academic.oup.com
There is now compelling evidence that gene by environment interactions are important in
the etiology of autism spectrum disorders (ASDs). However, the mechanisms by which …