Libraries of well-characterised components regulating gene expression levels are essential
to many synthetic biology applications. While widely available for the Gram-negative model …

Adaptation of cells to environmental changes requires dynamic interactions between
metabolic and regulatory networks, but studies typically address only one or a few layers of …

Bacillus subtilis can form various types of spatially organised communities on surfaces, such
as colonies, pellicles and submerged biofilms. These communities share similarities and …

When microbes lack the nutrients necessary for growth, they enter stationary phase. In cases
when energy sources are still present in the environment, they must decide whether to …

The availability of complete genome sequences and the definition of essential gene sets
were fundamental in the start of the genome engineering era. In a recent study, redundant …

Background Bacillus subtilis is an all-important Gram-positive bacterium of valuable
biotechnological utility that has been widely used to over-produce industrially and …

Abstract Background Bacillus subtilis, a Gram-positive organism, has been developed to be
an attractive expression platform to produce both secreted and cytoplasmic proteins owing …

In eukaryotes, RNA species originating from pervasive transcription are regulators of various
cellular processes, from the expression of individual genes to the control of cellular …

Bacillus subtilis is a widely used bacterial model to decipher biofilm formation, genetic
determinants and their regulation. For several years, studies were conducted on colonies or …

Complex regulatory programs control cell adaptation to environmental changes by setting
condition‐specific proteomes. In balanced growth, bacterial protein abundances depend on …