[HTML][HTML] Asthma in the era of COVID-19

S Assaf, H Stenberg, M Jesenak, SP Tarasevych… - Respiratory …, 2023 - Elsevier
Since its global invasion in 2019, COVID-19 has affected several aspects of patients' lives
and posed a significant impact on the health care system. Several patient populations were …

Probiotics in children with asthma

G Ciprandi, MA Tosca - Children, 2022 - mdpi.com
A type-2 immune response usually sustains wheezing and asthma in children. In addition,
dysbiosis of digestive and respiratory tracts is detectable in patients with wheezing and …

Obesity is the comorbidity more strongly associated for Covid-19 in Mexico. A case-control study

E Hernández-Garduño - Obesity research & clinical practice, 2020 - Elsevier
Some comorbidities are associated with severe coronavirus disease (Covid-19) but it is
unclear whether some increase susceptibility to Covid-19. In this case-control Mexican study …

[HTML][HTML] Early-life respiratory tract infections and the risk of school-age lower lung function and asthma: a meta-analysis of 150 000 European children

ER van Meel, SM Mensink-Bout… - European respiratory …, 2022 - Eur Respiratory Soc
Background Early-life respiratory tract infections might affect chronic obstructive respiratory
diseases, but conclusive studies from general populations are lacking. Our objective was to …

The Probiotics in Pediatric Asthma Management (PROPAM) Study in the Primary Care Setting: A Randomized, Controlled, Double‐Blind Trial with Ligilactobacillus salivarius …

L Drago, L Cioffi, M Giuliano, M Pane… - Journal of …, 2022 - Wiley Online Library
Background. Type‐2 inflammation commonly marks asthma in childhood. Also, gut and lung
dysbiosis is detectable in patients with asthma. Strain‐related probiotic supplementation …

Physiological microbial exposure transiently inhibits mouse lung ILC2 responses to allergens

KE Block, K Iijima, MJ Pierson, DA Walsh, R Tei… - Nature …, 2022 - nature.com
Lung group 2 innate lymphoid cells (ILC2s) control the nature of immune responses to
airway allergens. Some microbial products, including those that stimulate interferons, block …

An overview of asthma and COVID-19: protective factors against SARS-COV-2 in pediatric patients

M Liuzzo Scorpo, G Ferrante, S La Grutta - Frontiers in Pediatrics, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a pandemic infectious disease caused by severe
acute respiratory syndrome coronavirus SARS-COV-2. Aberrant innate immunity response …

A randomized, placebo-controlled, double-blinded, single-centre, phase IV trial to assess the efficacy and safety of OM-85 in children suffering from recurrent …

S Esposito, S Bianchini, S Bosis, C Tagliabue… - Journal of translational …, 2019 - Springer
Background Over many years, OM-85, a lysate of 21 common bacterial respiratory
pathogens, has been demonstrated to prevent respiratory recurrences in children. However …

Phenotypic and functional translation of IL33 genetics in asthma

ME Ketelaar, MA Portelli, FN Dijk, N Shrine… - Journal of Allergy and …, 2021 - Elsevier
Background Asthma is a complex disease with multiple phenotypes that may differ in
disease pathobiology and treatment response. IL33 single nucleotide polymorphisms …

HDAC4 induces the development of asthma by increasing Slug-upregulated CXCL12 expression through KLF5 deacetylation

W Wei, W Chen, N He - Journal of Translational Medicine, 2021 - Springer
Background Asthma is a frequently occurring respiratory disease with an increasing
incidence around the world. Airway inflammation and remodeling are important contributors …