Iron is a transition metal and essential constituent of almost all living cells and organisms. As
component of various metalloproteins it is involved in critical biochemical processes such as …

Production of minute concentrations of superoxide (O 2 radical dot−) and nitrogen monoxide
(nitric oxide, NO radical dot) plays important roles in several aspects of cellular signaling …

Background Iron homeostasis plays a positive role in articular cartilage health. Excessive
iron or iron overload can induce oxidative stress damage in chondrocytes and ferroptosis …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Biodegradable core− shell structured nanoparticles with a poly (β-amino ester)(PBAE) core
enveloped by a phospholipid bilayer shell were developed for in vivo mRNA delivery with a …

JC-1, a cationic fluorescent dye when added to living cells, is known to be localized
exclusively in mitochondria, particularly in good physiological conditions characterized by …

Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

Iron is an essential cofactor for important biological activities and biochemical reactions,
including the transport of oxygen via red blood cells and its reduction to water during …

Objective: Iron overload is common in elderly people which is associated with an increased
prevalence of osteoarthritis (OA), but the exact role of iron in the development of OA has not …

H2DCF-DA (dihydrodichlorofluorescein diacetate) is widely used to evaluate 'cellular
oxidative stress'. After passing through the plasma membrane, this lipophilic and non …