Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Genetically Engineered‐Cell‐Membrane Nanovesicles for Cancer Immunotherapy

Q Cheng, Y Kang, B Yao, J Dong, Y Zhu… - Advanced …, 2023 - Wiley Online Library
The advent of immunotherapy has marked a new era in cancer treatment, offering significant
clinical benefits. Cell membrane as drug delivery materials has played a crucial role in …

Genetically Engineered Cell Membrane‐Coated Magnetic Nanoparticles for High‐Performance Isolation of Circulating Tumor Cells

X Jiang, X Zhang, C Guo, B Ma, Z Liu… - Advanced Functional …, 2024 - Wiley Online Library
Circulating tumor cells (CTCs) are a crucial biomarker for early cancer diagnosis and
progress of cancer metastasis. However, the extremely rare CTCs with large amounts of …

Tumor-derived systems as novel biomedical tools—turning the enemy into an ally

N Desai, P Katare, V Makwana, S Salave… - Biomaterials …, 2023 - spj.science.org
Cancer is a complex illness that presents significant challenges in its understanding and
treatment. The classic definition," a group of diseases characterized by the uncontrolled …

Genetically Engineered Cellular Nanovesicles: Theories, Design and Perspective

Q Cheng, R Li, Y He, Y Zhu, Y Kang… - Advanced Functional …, 2024 - Wiley Online Library
The use of cellular nanovesicles (CNVs) is a groundbreaking innovation in biomedical
applications. Both natural extracellular vesicles (EVs) and artificial cell membrane …

Advanced Generation Therapeutics: Biomimetic Nanodelivery System for Tumor Immunotherapy

J Li, H Zeng, L Li, Q Yang, L He, M Dong - ACS nano, 2023 - ACS Publications
Tumor immunotherapy is a safe and effective strategy for precision medicine. However,
immunotherapy for most cancer cases still ends in failure, with the root causes of the …

Monophosphoryl lipid A-assembled nanovaccines enhance tumor immunotherapy

R Li, Y Hao, W Pan, W Wang, Y Min - Acta Biomaterialia, 2023 - Elsevier
Therapeutic cancer nanovaccines can induce strong antitumor immunity and establish long-
term immune memory and have shown potential for curing tumors in some clinical trials …

In-situ vaccination immunotherapy of colorectal cancer with STING agonist-integrated supramolecular nanovectors

X Liu, F Chen, M Saeed, X Li, H Zhang, J Zhang… - Nano Today, 2024 - Elsevier
The immunosuppressive tumor immune microenvironment and low tumor immunogenicity
invariably subvert the efficacy of cancer vaccine and the antitumor immunity. An alternative …

Biomimetic cell-derived nanoparticles: emerging platforms for cancer immunotherapy

T Hu, Y Huang, J Liu, C Shen, F Wu, Z He - Pharmaceutics, 2023 - mdpi.com
Cancer immunotherapy can significantly prevent tumor growth and metastasis by activating
the autoimmune system without destroying normal cells. Although cancer immunotherapy …

Genetically Engineered Cytomembrane Nanovaccines for Cancer Immunotherapy

Y Pan, X Wu, L Liu, C Zhao, J Zhang… - Advanced …, 2024 - Wiley Online Library
Cancer nanovaccines have attracted widespread attention by inducing potent cytotoxic T
cell responses to improve immune checkpoint blockade (ICB) therapy, while the lack of co …