Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Lanthanide probes for bioresponsive imaging

MC Heffern, LM Matosziuk, TJ Meade - Chemical reviews, 2014 - ACS Publications
The chemistry of the less familiar elements is a fascinating topic especially for the inorganic
minded. The lanthanides, or rare earths, comprise the 5d block of the periodic table and …

Chemical exchange saturation transfer (CEST): what is in a name and what isn't?

PCM Van Zijl, NN Yadav - Magnetic resonance in medicine, 2011 - Wiley Online Library
Chemical exchange saturation transfer (CEST) imaging is a relatively new magnetic
resonance imaging contrast approach in which exogenous or endogenous compounds …

Challenges for molecular magnetic resonance imaging

E Terreno, DD Castelli, A Viale, S Aime - Chemical reviews, 2010 - ACS Publications
Challenges for Molecular Magnetic Resonance Imaging | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most …

Alternatives to gadolinium-based metal chelates for magnetic resonance imaging

S Viswanathan, Z Kovacs, KN Green… - Chemical …, 2010 - ACS Publications
Magnetic resonance imaging (MRI) has been immensely valuable in diagnostic clinical
imaging over the last few decades owing to its exceptional spatial and anatomical …

Quantitative separation of CEST effect from magnetization transfer and spillover effects by Lorentzian-line-fit analysis of z-spectra

M Zaiß, B Schmitt, P Bachert - Journal of magnetic resonance, 2011 - Elsevier
Chemical exchange saturation transfer (CEST) processes in aqueous systems are
quantified by evaluation of z-spectra, which are obtained by acquisition of the water proton …

A review of responsive MRI contrast agents: 2005–2014

DV Hingorani, AS Bernstein… - Contrast media & …, 2015 - Wiley Online Library
This review focuses on MRI contrast agents that are responsive to a change in a
physiological biomarker. The response mechanisms are dependent on six physicochemical …

A review of hyperthermia combined with radiotherapy/chemotherapy on malignant tumors

W Rao, ZS Deng - Critical Reviews™ in Biomedical …, 2010 - dl.begellhouse.com
Therapeutic hyperthermia is a procedure that involves heating tissues to a higher
temperature level, typically ranging from 41 C to 45 C. Its combination with radiotherapy …

A concentration‐independent method to measure exchange rates in PARACEST agents

WT Dixon, J Ren, AJM Lubag… - Magnetic resonance …, 2010 - Wiley Online Library
The efficiency of chemical exchange dependent saturation transfer (CEST) agents is largely
determined by their water or proton exchange kinetics, yet methods to measure such …

Saturation power dependence of amide proton transfer image contrasts in human brain tumors and strokes at 3 T

X Zhao, Z Wen, F Huang, S Lu, X Wang… - Magnetic resonance …, 2011 - Wiley Online Library
Amide proton transfer (APT) imaging is capable of detecting mobile cellular proteins and
peptides in tumor and monitoring pH effects in stroke, through the saturation transfer …