For people living in developed countries life span is growing at a faster pace than ever. One
of the main reasons for such success is attributable to the introduction and extensive use in …

Antibacterial resistance is a renewed public health plague in modern times, and the COVID-
19 pandemic has rekindled this problem. Changes in antibiotic prescribing behavior …

The emergence and global expansion of hyper-virulent and multidrug resistant (MDR)
Klebsiella pneumoniae is an increasing healthcare threat worldwide. The epidemiology of …

Objectives Although hypervirulent Klebsiella pneumoniae (hvKp) is an increasing public
health problem, there remains limited epidemiological information regarding hvKp infections …

Klebsiella pneumoniae causes community-and healthcare-associated infections in children
and adults. Globally in 2019, an estimated 1.27 million (95% Uncertainty Interval [UI]: 0.91 …

Carbapanem-resistant Klebsiella pneumoniae is a globally healthcare crisis. The
distribution of plasmids carrying carbapenemase genes among K. pneumoniae poses a …

Antibiotic and metal resistance can occur together in the environment and can be linked by
the same detoxication mechanism (cross-resistance). The understanding of this linkage may …

Mobile tigecycline resistance (MTR) threatens the clinical efficacy of the salvage antibiotic,
tigecycline (TIG) used in treating deadly infections in humans caused by superbugs …

Pneumonia is a common comorbidity in patients with severe traumatic brain injury (TBI), and
is associated with increased morbidity and mortality. In this study, we established a model of …

Klebsiella pneumoniae (Kp) is a human symbiotic opportunistic pathogen capable of
causing severe hospital-based infections and community-acquired infections. The problem …