Bioactive constituents and toxicological evaluation of selected antidiabetic medicinal plants of Saudi Arabia

AS Alqahtani, R Ullah, AA Shahat - … Based Complementary and …, 2022 - Wiley Online Library
The purpose of this review is to summarize the available antidiabetic medicinal plants in the
Kingdom of Saudi Arabia with its phytoconstituents and toxicological findings supporting by …

[HTML][HTML] The application of metabolomics in investigating anti-diabetic activity of medicinal plants

M Hasanpour, M Iranshahy, M Iranshahi - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetes mellitus is the most prevalent endocrine disease in the world and is likely to be the
major epidemic in human history. In current years, many modern anti-diabetic medicines …

Oat β-glucan ameliorates diabetes in high fat diet and streptozotocin-induced mice by regulating metabolites

H Guo, H Wu, X Kong, N Zhang, H Li, X Dong… - The Journal of Nutritional …, 2023 - Elsevier
Oats are widely distributed worldwide and oat β-glucan has positive effects on human
health. Particularly, oat β-glucan is reported to be beneficial in the management of type 2 …

Antidiabetic effect of Ardisia elliptica extract and its mechanisms of action in STZ-NA-induced diabetic rat model via 1H-NMR-based metabolomics

PL Wong, NKZ Zolkeflee, NS Ramli, CP Tan… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Ardisia elliptica Thunb.(AE)(Primulaceae) is a
medicinal plant found in the Malay Peninsula and has been traditionally used to treat …

Ecotoxicological impact of heavy metals on wild mud crabs (Scylla olivacea) in Malaysia: An integrative approach of omics, molecular docking and human risk …

NSM Razali, M Ikhwanuddin, M Maulidiani… - Science of The Total …, 2024 - Elsevier
Mud crab, one of the aquatic organisms found in estuary areas, has become a significant
economic source of seafood for communities due to its delectable taste. However, they face …

Hypoglycemic effects of Auricularia auricula polysaccharides on high fat diet and streptozotocin-induced diabetic mice using metabolomics analysis

N Liu, X Chen, J Song, M Chen, P Gong, W Jia, G Li - Food & Function, 2021 - pubs.rsc.org
This study evaluated the hypoglycemic effect of Auricularia auricula polysaccharides (AAPs)
on streptozotocin-induced type 2 diabetes mellitus (T2DM) mice using metabolomic …

Effect of virgin avocado oil on diet‐induced hypercholesterolemia in rats via 1H NMR‐based metabolomics approach

CX Tan, GH Chong, H Hamzah… - Phytotherapy …, 2018 - Wiley Online Library
Hypercholesterolemia is a major risk factor for the initiation and development of
nonalcoholic fatty liver disease and atherosclerosis. The present study evaluated the …

Integrated gut microbiota and urine metabolite analyses of T2DM with NAFLD rat model

J Qin, X Ling, Q Wang, Z Huang, B Guo… - Applied Biochemistry …, 2023 - Springer
Abstract Globally 80% type 2 diabetes mellitus (T2DM) patients suffer nonalcoholic fatty liver
disease (NAFLD). The interplay of gut microbiota and endogenous metabolic networks has …

Detection of bioactive compounds in persimmon (Diospyros kaki) using UPLC-ESI-Orbitrap-MS/MS and fluorescence analyses

M Maulidiani, NA Abdul-Hamid, F Abas, YS Park… - Microchemical …, 2019 - Elsevier
Persimmon (Diospyros kaki L.) contains a number of metabolites, especially polyphenols
and carotenoids, and persimmon is one of the most healthy fruits linking to a diet with …

Potential therapeutic mechanism of traditional Chinese medicine on diabetes in rodents: a review from an NMR-based metabolomics perspective

Y Huang, J Lu, Q Zhao, J Chen, W Dong, M Lin… - Molecules, 2022 - mdpi.com
Traditional Chinese medicine (TCM) has been used to treat diabetes for a long time, but its
application has not been widely accepted due to unstandardized product quality and …