Cerebellum lecture: the cerebellar nuclei—core of the cerebellum

JM Kebschull, F Casoni, GG Consalez, D Goldowitz… - The Cerebellum, 2024 - Springer
The cerebellum is a key player in many brain functions and a major topic of neuroscience
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …

[HTML][HTML] Impact of Intrauterine Insults on Fetal and Postnatal Cerebellar Development in Humans and Rodents

JAW Westerhuis, J Dudink, BECA Wijnands… - Cells, 2024 - mdpi.com
Many children suffer from neurodevelopmental aberrations that have long-term effects. To
understand the consequences of pathological processes during particular periods in …

Novel cerebello-amygdala connections provide missing link between cerebellum and limbic system

SJ Jung, K Vlasov, AF D'Ambra, A Parigi… - Frontiers in systems …, 2022 - frontiersin.org
The cerebellum is emerging as a powerful regulator of cognitive and affective processing
and memory in both humans and animals and has been implicated in affective disorders …

Cerebellum involvement in dystonia during associative motor learning: insights from a data-driven spiking network model

A Geminiani, A Mockevičius, E D'Angelo… - Frontiers in Systems …, 2022 - frontiersin.org
Dystonia is a movement disorder characterized by sustained or intermittent muscle
contractions causing abnormal, often repetitive movements, postures, or both. Although …

Lobule-related action potential shape-and history-dependent current integration in purkinje cells of adult and developing mice

GC Beekhof, M Schonewille - Cells, 2023 - mdpi.com
Purkinje cells (PCs) are the principal cells of the cerebellar cortex and form a central
element in the modular organization of the cerebellum. Differentiation of PCs based on gene …

Molecular identity and location influence Purkinje cell vulnerability in autosomal-recessive spastic ataxia of charlevoix-saguenay mice

B Toscano Márquez, AA Cook, M Rice… - Frontiers in Cellular …, 2021 - frontiersin.org
Patterned cell death is a common feature of many neurodegenerative diseases. In patients
with autosomal-recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) and mouse …

Converging and Diverging Cerebellar Pathways for Motor and Social Behaviors in Mice

ME van der Heijden - The Cerebellum, 2024 - Springer
Evidence from clinical and preclinical studies has shown that the cerebellum contributes to
cognitive functions, including social behaviors. Now that the cerebellum's role in a wider …

Whisker kinematics in the cerebellum

P Zhai, V Romano, G Soggia, S Bauer… - The Journal of …, 2024 - Wiley Online Library
The whisker system is widely used as a model system for understanding sensorimotor
integration. Purkinje cells in the crus regions of the cerebellum have been reported to …

Sleep-state dependent cerebellar processing in adult mice

CB Canto, S Bauer, TM Hoogland, HH Hoedemaker… - bioRxiv, 2023 - biorxiv.org
The cerebellum is important for motor performance and adaptation as well as cognition.
Sleep is essential for optimizing of all these functions, but it remains to be elucidated how …

Purkinje cell ablation and Purkinje cell‐specific deletion of Tsc1 in the developing cerebellum strengthen cerebellothalamic synapses

H Nishiyama, N Nishiyama… - The Journal of …, 2024 - Wiley Online Library
Cerebellar damage early in life often causes long‐lasting motor, social and cognitive
impairments, suggesting the roles of the cerebellum in developing a broad spectrum of …