A research agenda for ageing in China in the 21st century: Focusing on basic and translational research, long-term care, policy and social networks
One of the key issues facing public healthcare is the global trend of an increasingly ageing
society which continues to present policy makers and caregivers with formidable healthcare …
society which continues to present policy makers and caregivers with formidable healthcare …
Nongenomic activities of vitamin D
MA Żmijewski - Nutrients, 2022 - mdpi.com
Vitamin D shows a variety of pleiotropic activities which cannot be fully explained by the
stimulation of classic pathway-and vitamin D receptor (VDR)-dependent transcriptional …
stimulation of classic pathway-and vitamin D receptor (VDR)-dependent transcriptional …
SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1
A recent mutation analysis suggested that Non-Structural Protein 6 (NSP6) of the Severe
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a key determinant of the viral …
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a key determinant of the viral …
Vitamin D receptor (s): In the nucleus but also at membranes?
MA Zmijewski, C Carlberg - Experimental Dermatology, 2020 - Wiley Online Library
The genomic actions of the vitamin D are mediated via its biologically most potent metabolite
1α, 25‐dihydroxyvitamin D3 (1, 25 (OH) 2D3) and the transcription factor vitamin D receptor …
1α, 25‐dihydroxyvitamin D3 (1, 25 (OH) 2D3) and the transcription factor vitamin D receptor …
[HTML][HTML] Vitamin D-cathelicidin axis: at the crossroads between protective immunity and pathological inflammation during infection
Vitamin D signaling plays an essential role in innate defense against intracellular
microorganisms via the generation of the antimicrobial protein cathelicidin. In addition to …
microorganisms via the generation of the antimicrobial protein cathelicidin. In addition to …
Double‐pronged antimicrobial agents based on a donor‐π‐acceptor type aggregation‐induced emission luminogen
Y Wu, J Li, Z Shen, D Wang, R Dong… - Angewandte …, 2022 - Wiley Online Library
Novel antibacterial agents are urgently needed to control the infections induced by multidrug‐
resistant (MDR) bacteria. Herein, we rationally designed and facilely synthesized a new D‐π …
resistant (MDR) bacteria. Herein, we rationally designed and facilely synthesized a new D‐π …
ERp57/PDIA3: new insight
S Chichiarelli, F Altieri, G Paglia, E Rubini… - Cellular & Molecular …, 2022 - Springer
The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although
predominantly located in the endoplasmic reticulum (ER), has indeed been found in other …
predominantly located in the endoplasmic reticulum (ER), has indeed been found in other …
Vitamin D in autophagy signaling for health and diseases: Insights on potential mechanisms and future perspectives
SK Bhutia - The Journal of Nutritional Biochemistry, 2022 - Elsevier
Vitamin D regulates the pleiotropic effect to maintain cellular homeostasis and
epidemiological evidence establishes an association between vitamin D deficiency and …
epidemiological evidence establishes an association between vitamin D deficiency and …
LOX-1 acts as an N6-methyladenosine-regulated receptor for Helicobacter pylori by binding to the bacterial catalase
The role of N6-methyladenosine (m6A) modification of host mRNA during bacterial infection
is unclear. Here, we show that Helicobacter pylori infection upregulates host m6A …
is unclear. Here, we show that Helicobacter pylori infection upregulates host m6A …
Role of endolysosomes in severe acute respiratory syndrome coronavirus-2 infection and coronavirus disease 2019 pathogenesis: implications for potential …
N Khan, X Chen, JD Geiger - Frontiers in pharmacology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an enveloped, single-
stranded RNA virus. Humans infected with SARS-CoV-2 develop a disease known as …
stranded RNA virus. Humans infected with SARS-CoV-2 develop a disease known as …