Antibiotic resistance is a major global health challenge and, worryingly, several key Gram
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Importance The effectiveness of selective decontamination of the digestive tract (SDD) in
critically ill adults receiving mechanical ventilation is uncertain. Objective To determine …

Background Estimating attributable mortality of ventilator-associated pneumonia has been
hampered by confounding factors, small sample sizes, and the difficulty of doing relevant …

EXECUTIVE SUMMARY Since the initial 1996 American Thoracic Society (ATS) guideline
on nosocomial pneumonia, a number of new developments have appeared, mandating a …

This report updates, expands, and replaces the previously published CDC" Guideline for
Prevention of Nosocomial Pneumonia". The new guidelines are designed to reduce the …

Background: Ventilator-associated pneumonia (VAP) is the most common nosocomial
infection in critically ill patients. The clinical and economic consequences of VAP are …

The oral cavity of healthy individuals contains hundreds of different bacterial, viral, and
fungal species. Many of these can associate to form biofilms, which are resistant to …

Background: The purpose of this review was to investigate evidence for a possible
etiological association between oral health and pneumonia or other respiratory diseases …

While critically ill patients experience a life-threatening illness, they commonly contract
ventilator-associated pneumonia. This nosocomial infection increases morbidity and likely …