Immunotherapy in testicular germ cell tumors

K Kalavska, S Schmidtova, M Chovanec… - Frontiers in …, 2020 - frontiersin.org
Testicular germ cell tumors (TGCTs) are malignancies with very high curative potential even
in metastatic settings, mainly due to the introduction of cisplatin in the treatment of this …

Immune-related mechanisms and immunotherapy in extragonadal germ cell tumors

W Xiu, J Pang, Y Hu, H Shi - Frontiers in Immunology, 2023 - frontiersin.org
Purpose of review Extragonadal germ cell tumors (EGCTs) are relatively rare tumors,
accounting for 1%–5% of all GCTs. In this review, we summarize the current research …

SLU7: a new hub of gene expression regulation—from epigenetics to protein stability in health and disease

M Gárate-Rascón, M Recalde, C Rojo… - International Journal of …, 2022 - mdpi.com
SLU7 (Splicing factor synergistic lethal with U5 snRNA 7) was first identified as a splicing
factor necessary for the correct selection of 3′ splice sites, strongly impacting on the …

Immune mechanisms and possible immune therapy in testicular germ cell tumours

M Chovanec, J Mardiak, M Mego - Andrology, 2019 - Wiley Online Library
Background Testicular germ cell tumours (GCT s) are the only universally curable solid
malignancy. The long‐term cure rate of> 95% is attributed to the extraordinary sensitivity to …

Unveiling the Immunogenicity of Ovarian Tumors as the Crucial Catalyst for Therapeutic Success

GM Rodriguez, E Yakubovich, BC Vanderhyden - Cancers, 2023 - mdpi.com
Simple Summary Tumor immunogenicity is one of the main factors influencing responses to
cancer therapies and long-lasting antitumoral immunity. In this review, we will cover how …

Aberrant DNA Methylation in Human Hepatocellular Carcinoma

R Khan, U Zakir - Pakistan Journal of Medicine and Dentistry, 2021 - ojs.zu.edu.pk
Essential epigenetic mechanism ie, DNA methylation in humans is being continuously
acknowledged as a hallmark of various cancer. Hypo-methylation and CpG hyper …