Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence suggests that RNA is not only functional as a messenger between DNA and protein but also …
RS Zhou, EX Zhang, QF Sun, ZJ Ye, JW Liu, DH Zhou… - BMC cancer, 2019 - Springer
Background Numerous studies have highlighted that long non-coding RNAs (lncRNAs) can bind to microRNA (miRNA) sites as competing endogenous RNAs (ceRNAs), thereby …
The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to being defined as a category of genetic elements, leaving its mark on the field of cancer …
In addition to mutations or aberrant expression in the protein-coding genes, mutations and misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …
Neutrophils, eosinophils and 'classical'monocytes collectively account for about 70% of human blood leukocytes and are among the shortest-lived cells in the body,. Precise …
L Zhang, X Meng, X Zhu, D Yang, R Chen, Y Jiang… - Molecular cancer, 2019 - Springer
There is growing evidence that regions of the genome that cannot encode proteins play an important role in diseases. These regions are usually transcribed into long non-coding …
L Wang, Y Zhao, X Bao, X Zhu, YK Kwok, K Sun… - Cell research, 2015 - nature.com
Emerging studies document the roles of long non-coding RNAs (LncRNAs) in regulating gene expression at chromatin level but relatively less is known how they regulate DNA …
C Kanduri - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2016 - Elsevier
Genomic imprinting has been a great resource for studying transcriptional and post- transcriptional-based gene regulation by long noncoding RNAs (lncRNAs). In this article, I …
H Ma, T Hu, W Tao, J Tong, Z Han… - Cell Research, 2023 - nature.com
Inflammatory bowel diseases (IBD) are known to have complex, genetically influenced etiologies, involving dysfunctional interactions between the intestinal immune system and …