[HTML][HTML] Conserved and Unique Roles of bHLH-PAS Transcription Factors in Insects–From Clock to Hormone Reception

S Tumova, D Dolezel, M Jindra - Journal of Molecular Biology, 2024 - Elsevier
A dozen bHLH-PAS transcription factors have evolved since the dawn of the animal
kingdom; nine of them have mutual orthologs between arthropods and vertebrates. These …

Unique peptidic agonists of a juvenile hormone receptor with species-specific effects on insect development and reproduction

S Tumova, M Milacek, I Šnajdr… - Proceedings of the …, 2022 - National Acad Sciences
Juvenile hormones (JHs) control insect metamorphosis and reproduction. JHs act through a
receptor complex consisting of methoprene-tolerant (Met) and taiman (Tai) proteins to …

[HTML][HTML] Agonist-dependent action of the juvenile hormone receptor

M Jindra, S Tumova, L Bittova, R Tuma… - Current Opinion in Insect …, 2024 - Elsevier
Juvenile hormone (JH) signaling is affected at the gene regulatory level by receptors of the
bHLH-PAS transcription factor family. The sesquiterpenoid hormones and their synthetic …

Hormone-related genes heterochronically and modularly regulate neotenic differentiation in termites

K Oguchi, S Koshikawa, T Miura - Developmental Biology, 2022 - Elsevier
Caste development in social insects requires the coordination of molting and
metamorphosis during postembryonic development. In termites, ie, hemimetabolous …

Ligand‐dependent protein interactions of the juvenile hormone receptor captured in real time

S Tumova, M Jindra - The FEBS Journal, 2023 - Wiley Online Library
Juvenile hormone (JH) signalling provides vital regulatory functions during insect
development via transcriptional regulation of genes critical for the progression of …

Establishment of a testing system for juvenoids that disturb the sex determination system of Daphnia, based on a molecular interaction of ligands and the JH receptor

H Miyakawa, T Iguchi - Current Opinion in Toxicology, 2023 - Elsevier
Bioassays are the most common method of evaluating toxic effects of chemicals on living
organisms. However, since simple bioassays cannot provide information on mechanisms of …

Synthesis of 1, 4‐benzodioxan derivatives and the evaluation of their biological activity as a novel juvenile hormone signaling inhibitor

K Furuta, N Yamada, T Kayukawa - Pest Management Science, 2023 - Wiley Online Library
BACKGROUND Juvenile hormone (JH) signaling inhibitors may be used as insect growth
regulators because of their ability to control metamorphosis and reproduction in insects by …

Unique and Common Agonists Activate the Insect Juvenile Hormone Receptor and the Human AHR

D Sedlak, R Tuma, JN Kolla, RB Mokhamatam… - Journal of Molecular …, 2025 - Elsevier
Transcription factors of the bHLH-PAS family play vital roles in animal development,
physiology, and disease. Two members of the family require binding of low-molecular …

[引用][C] The German cockroach as a model in insect development and reproduction in an endocrine context

X Belles, JL Maestro, MD Piulachs - 2024 - Elsevier