Tensegrity, cellular biophysics, and the mechanics of living systems

DE Ingber, N Wang, D Stamenović - Reports on Progress in …, 2014 - iopscience.iop.org
The recent convergence between physics and biology has led many physicists to enter the
fields of cell and developmental biology. One of the most exciting areas of interest has been …

An integrated cytoskeletal model of neurite outgrowth

KE Miller, DM Suter - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Neurite outgrowth underlies the wiring of the nervous system during development and
regeneration. Despite a significant body of research, the underlying cytoskeletal mechanics …

Balance of osmotic pressures determines the nuclear-to-cytoplasmic volume ratio of the cell

D Deviri, SA Safran - … of the National Academy of Sciences, 2022 - National Acad Sciences
The volume of the cell nucleus varies across cell types and species and is commonly
thought to be determined by the size of the genome and degree of chromatin compaction …

Confocal reference free traction force microscopy

M Bergert, T Lendenmann, M Zündel, AE Ehret… - Nature …, 2016 - nature.com
The mechanical wiring between cells and their surroundings is fundamental to the
regulation of complex biological processes during tissue development, repair or pathology …

Experimental demonstration of localized plasmonic structured illumination microscopy

JL Ponsetto, A Bezryadina, F Wei, K Onishi, H Shen… - ACS …, 2017 - ACS Publications
Super-resolution imaging methods such as structured illumination microscopy and others
have offered various compromises between resolution, imaging speed, and biocompatibility …

Combined atomic force microscopy (AFM) and traction force microscopy (TFM) reveals a correlation between viscoelastic material properties and contractile prestress …

N Schierbaum, J Rheinlaender, TE Schäffer - Soft Matter, 2019 - pubs.rsc.org
Living cells exhibit a complex mechanical behavior, whose underlying mechanisms are still
largely unknown. Emerging from the molecular structure and dynamics of the cytoskeleton …

Multiscale elasticity mapping of biological samples in 3D at optical resolution

K Regan, R LeBourdais, R Banerji, S Zhang… - Acta Biomaterialia, 2024 - Elsevier
The mechanical properties of biological tissues have emerged as an integral determinant of
tissue function in health and disease. Nonetheless, characterizing the elasticity of biological …

Measurement of subcellular force generation in neurons

M O'Toole, P Lamoureux, KE Miller - Biophysical journal, 2015 - cell.com
Forces are important for neuronal outgrowth during the initial wiring of the nervous system
and after trauma, yet subcellular force generation over the microtubule-rich region at the rear …

Keloid progression: a stiffness gap hypothesis

C Huang, L Liu, Z You, B Wang, Y Du… - International wound …, 2017 - Wiley Online Library
Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal
progression and post‐surgical recurrence and histologically by the accumulation of collagen …

Spatial correlation of cell stiffness and traction forces in cancer cells measured with combined SICM and TFM

J Rheinlaender, H Wirbel, TE Schäffer - Rsc Advances, 2021 - pubs.rsc.org
The mechanical properties of cancer cells at the single-cell and the subcellular level might
be the key for answering long-standing questions in the diagnosis and treatment of cancer …