HOXA9 versus HOXB9; particular focus on their controversial role in tumor pathogenesis

A Hjazi, SA Jasim, AMB Al-Dhalimy, P Bansal… - Journal of Applied …, 2024 - Springer
The Homeobox (HOX) gene family is essential to regulating cellular processes because it
maintains the exact coordination required for tissue homeostasis, cellular differentiation, and …

HOXB9 Overexpression Promotes Colorectal Cancer Progression and Is Associated with Worse Survival in Liver Resection Patients for Colorectal Liver Metastases

E Martinou, C Moller-Levet, D Karamanis… - International journal of …, 2022 - mdpi.com
As is known, HOXB9 is an important factor affecting disease progression and overall survival
(OS) in cancer. However, its role in colorectal cancer (CRC) remains unclear. We aimed to …

Identification of unique rectal cancer-specific subtypes

B Kisakol, A Matveeva, M Salvucci, A Kel… - British Journal of …, 2024 - nature.com
Background Existing colorectal cancer subtyping methods were generated without much
consideration of potential differences in expression profiles between colon and rectal …

Homeobox B9 promotes colon cancer progression by targeting SRSF3

L Yuan, F Cheng, Z Wu, X Li, W Shen - Digestive Diseases and Sciences, 2023 - Springer
Abstract Background Homeobox B9 (HOXB9) is one of the HOX family of transcription
factors that are essential for cancer development and embryonic growth. However, the …

The diagnostic potential of miR-196a-1 in colorectal cancer

B Mehrjoei, L Haghnazari, H Bashiri, N Rezvani - BMC cancer, 2024 - Springer
Background Colorectal cancer (CRC) is a common malignancy worldwide. MicroRNAs
(miRNAs) are important epigenetic alterations that notably impact various physiological and …

[HTML][HTML] PBX4 functions as a potential novel oncopromoter in colorectal cancer: a comprehensive analysis of the PBX gene family

EG Martinou, CS Moller-Levet… - American journal of …, 2022 - ncbi.nlm.nih.gov
Pre-B-cell leukaemia (PBX) is a transcription factor family (PBX1, PBX2, PBX3 and PBX4)
that regulates important cellular functions and has been identified to be involved in human …

The effect and apoptosis mechanism of 6-methoxyflavone in HeLa cells

C Zhang, Y Quan, Y Bai, L Yang, Y Yang - Biomarkers, 2022 - Taylor & Francis
Introduction Tumour cell apoptosis is a crucial indicator for judging the antiproliferative
effects of anti-cancer drugs. The detection of optical and macromolecular biomarkers is the …