Major depressive disorder is a highly debilitating psychiatric disorder involving the
dysfunction of different cell types in the brain. Microglia are the predominant resident …

Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …

Neuroinflammation in the central nervous system (CNS) is an important subject of
neuroimmunological research. Emerging evidence suggests that neuroinflammation is a key …

Spinal cord injury (SCI), for which there currently is no cure, is a heavy burden on patient
physiology and psychology. The microenvironment of the injured spinal cord is complicated …

Microglia, the brain's immune cells, maintain homeostasis and sense pathological changes
by continuously surveying the parenchyma with highly motile large processes. Here, we …

Macrophages from the peripheral circulation and those derived from resident microglia are
among the main effector cells of the inflammatory response that follows spinal cord trauma …

Microglia are highly dynamic immune cells of the CNS and their dynamism is proposed to be
regulated by neuronal activities. However, the mechanisms underlying neuronal regulation …

Microglia were recently shown to play unexpected roles in normal brain development and
adult physiology. This has begun to dramatically change our view of these resident …

Animal studies are now showing the exciting potential to achieve significant functional
recovery following central nervous system (CNS) injury by manipulating both the inefficient …

Microglia and peripheral monocytes contribute to hypersensitivity in rodent models of
neuropathic pain. However, the precise respective function of microglia and peripheral …