[HTML][HTML] Fluoride exposure and cognitive neurodevelopment: Systematic review and dose-response meta-analysis

F Veneri, M Vinceti, L Generali, ME Giannone… - Environmental …, 2023 - Elsevier
Many uncertainties still surround the possible harmful effect of fluoride exposure on
cognitive neurodevelopment in children. The aim of this systematic review and meta …

Fluoride exposure and children's IQ scores: a systematic review and meta-analysis

KW Taylor, SE Eftim, CA Sibrizzi, RB Blain… - JAMA …, 2025 - jamanetwork.com
Importance Previous meta-analyses suggest that fluoride exposure is adversely associated
with children's IQ scores. An individual's total fluoride exposure comes primarily from fluoride …

[HTML][HTML] Critical windows of fluoride neurotoxicity in Canadian children

L Farmus, C Till, R Green, R Hornung, EAM Mier… - Environmental …, 2021 - Elsevier
Background Fluoride has been associated with IQ deficits during early brain development,
but the period in which children are most sensitive is unknown. Objective We assessed …

Fluoride exposure induces mitochondrial damage and mitophagy via activation of the IL-17A pathway in hepatocytes

Y Zhao, J Wang, J Zhang, Z Sun, R Niu… - Science of the Total …, 2022 - Elsevier
As an environmental toxicant, the damage of fluoride to the body has attracted global
attention. Because liver is an essential organ for fluoride accumulation and damage. Our …

Domain-specific effects of prenatal fluoride exposure on child IQ at 4, 5, and 6–12 years in the ELEMENT cohort

CV Goodman, M Bashash, R Green, P Song… - Environmental …, 2022 - Elsevier
Objective Prenatal exposure to fluoride has been associated with adverse
neurodevelopmental outcomes. However, the neuropsychological profile of fluoride's …

Fluoride exposure provokes mitochondria-mediated apoptosis and increases mitophagy in osteocytes via increasing ROS production

Y Zhang, F Dong, Z Wang, B Xu, T Zhang… - … Trace Element Research, 2023 - Springer
Fluoride is a persistent environmental pollutant, and its excessive intake causes skeletal and
dental fluorosis. However, few studies focused on the effects of fluoride on osteocytes …

[HTML][HTML] The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity

J Zhang, Y Tang, Z Hu, W Xu, Y Ma, P Xu… - Ecotoxicology and …, 2023 - Elsevier
Fluoride is capable of inducing developmental neurotoxicity; regrettably, the mechanism is
obscure. We aimed to probe the role of lysosomal biogenesis disorder in developmental …

Dietary micronutrients from zygote to senility: updated review of minerals' role and orchestration in human nutrition throughout life cycle with sex differences

MA Farag, S Hamouda, S Gomaa, AA Agboluaje… - Nutrients, 2021 - mdpi.com
Micronutrients such as selenium, fluoride, zinc, iron, and manganese are minerals that are
crucial for many body homeostatic processes supplied at low levels. The importance of …

Regional and racial/ethnic inequalities in public drinking water fluoride concentrations across the US

R Hefferon, DE Goin, JA Sarnat, AE Nigra - Journal of exposure science …, 2024 - nature.com
Abstract Background Although the US Centers for Disease Control and Prevention (CDC)
considers fluoridation of community water systems (CWSs) to be a major public health …

Associations between urinary, dietary, and water fluoride concentrations among children in Mexico and Canada

R Green, C Till, A Cantoral, B Lanphear… - Toxics, 2020 - mdpi.com
Fluoride, which may be toxic to the developing brain, is added to salt in Mexico and drinking
water in Canada to prevent dental caries. We compared childhood urinary fluoride (CUF) …