The NACHT, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …

Cardiac fibrosis is a common pathophysiologic companion of most myocardial diseases,
and is associated with systolic and diastolic dysfunction, arrhythmogenesis, and adverse …

In radiation therapy for cancer, the therapeutic ratio represents an optimal balance between
tumor control and normal tissue complications. As improvements in the therapeutic arsenal …

Cardiovascular diseases are the leading cause of death worldwide. Research in the last two
decades has emphasized the inflammatory process as a key component in the …

Acute myocardial infarction (AMI) is associated with the induction of a sterile inflammatory
response that leads to further injury. The NACHT, leucine-rich repeat, and pyrin domain …

Heart failure (HF) is the leading cause of morbidity and mortality in developed countries, and
it is the primary cause of mortality in the elderly worldwide. The processes of inflammatory …

Heart disease is an increasingly recognized, serious late effect of radiation exposure, most
notably among breast cancer and Hodgkin's disease survivors, as well as the Hiroshima and …

Monkeypox virus (MPV) is known to inflict injuries and, in some cases, lead to fatalities in
humans. However, the underlying mechanisms responsible for its pathogenicity remain …

Radiotherapy is one of the mainstream treatment modalities for several malignancies.
However, radiation-induced injury to surrounding normal tissues limits its efficacy. The …

The increasing risk of long-term adverse effects from radiotherapy on the cardiovascular
structure is receiving increasing attention. However, the mechanisms underlying this …