Nuclear receptors are ancient ligand-regulated transcription factors that control key
metabolic and developmental pathways. The fruitfly Drosophila melanogaster has only 18 …

During postembryonic life, hormones, including ecdysteroids, juvenile hormones, insulin-like
peptides, and activin/TGFβ ligands act to transform the larval nervous system into an adult …

The steroid hormone 20-hydroxyecdysone and its EcR/USP receptor are vital during
arthropod development for coordinating molting and metamorphosis. Traditionally, little …

Ecdysone receptor (EcR) is the primary regulator of the ecdysteroid signalling pathway, a
critical pathway that directly links to moulting. In addition, EcR also regulates growth …

In 1974, Ashburner and colleagues postulated a model to explain the control of the puffing
sequence on Drosophila polytene chromosomes initiated by the molting hormone 20 …

A heterodimeric complex of two nuclear receptors, the ecdysone receptor (ECR) and
ultraspiracle (USP), transduces 20-hydroxyecdysone (20E) signaling to modulate insect …

Publisher Summary This chapter examines the information gathered about the ecdysteroid
receptor at three levels and provides brief descriptions and references for the tools used to …

Background 20-hydroxyecdysone (20E) and its receptor complex ecdysone receptor (EcR)
and ultraspiracle (USP) play a crucial role in controlling development, metamorphosis …

Although it has been well established that histone acetyltransferases (HATs) are involved in
the modulation of chromatin structure and gene transcription, there is only little information …

Ecdysteroids regulate insect growth and development through a heterodimeric complex of
nuclear receptors consisting of ecdysone receptor (EcR) and ultraspiracle (USP). In the red …