Mesenchymal stem cell-derived exosomes as a new therapeutic strategy in the brain tumors

E Ghasempour, S Hesami, E Movahed… - Stem Cell Research & …, 2022 - Springer
Brain tumors are one of the most mortal cancers, leading to many deaths among kids and
adults. Surgery, chemotherapy, and radiotherapy are available options for brain tumor …

Exosomes as rheumatoid arthritis diagnostic biomarkers and therapeutic agents

R Heydari, F Koohi, M Rasouli, K Rezaei… - Vaccines, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder that causes systemic
inflammation, autoimmunity, and joint abnormalities that result in permanent disability …

The current landscape of glioblastoma biomarkers in body fluids

S Zanganeh, E Abbasgholinejad, M Doroudian… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma is a highly aggressive brain cancer, and early detection and
accurate diagnosis are crucial for effective treatment. Traditional diagnostic methods have …

Extracellular vesicles and exosomes: novel insights and perspectives on lung cancer from early detection to targeted treatment

S Rahimian, H Najafi, B Afzali, M Doroudian - Biomedicines, 2024 - mdpi.com
Lung cancer demands innovative approaches for early detection and targeted treatment. In
addressing this urgent need, exosomes play a pivotal role in revolutionizing both the early …

Nanocarriers: A novel strategy for the delivery of CRISPR/Cas systems

F Hejabi, MS Abbaszadeh, S Taji, A O'Neill… - Frontiers in …, 2022 - frontiersin.org
In recent decades, clustered regularly interspaced short palindromic repeat/CRISPR-
associated protein (CRISPR/Cas) has become one of the most promising genome-editing …

Exosome-based immunotherapy as an innovative therapeutic approach in melanoma

S Babaei, M Fadaee, H Abbasi-Kenarsari… - Cell Communication and …, 2024 - Springer
The malignant form of melanoma is one of the deadliest human cancers that accounts for
almost all of the skin tumor-related fatalities in its later stages. Achieving an exhaustive …

Not all nebulizers are created equal: Considerations in choosing a nebulizer for aerosol delivery during mechanical ventilation

R MacLoughlin, I Martin-Loeches - Expert Review of Respiratory …, 2023 - Taylor & Francis
Introduction Aerosol therapy is commonly prescribed in the mechanically ventilated patient.
Jet nebulizers (JN) and vibrating mesh nebulizers (VMN) are the most common nebulizer …

Advancements in engineered mesenchymal stem cell exosomes for chronic lung disease treatment

Z Zhai, T Cui, J Chen, X Mao, T Zhang - Journal of Translational Medicine, 2023 - Springer
Chronic lung diseases include an array of conditions that impact airways and lung
structures, leading to considerable societal burdens. Mesenchymal stem cells (MSCs) and …

Therapeutic Applications of Stem Cell-Derived Exosomes

OAAY Abdulmalek, KH Husain, HKAA AlKhalifa… - International Journal of …, 2024 - mdpi.com
Exosomes are extracellular vesicles of endosomal origin, ranging from 30 to 150 nm in
diameter, that mediate intercellular transfer of various biomolecules, such as proteins, lipids …

Exosome-based therapies for inflammatory disorders: a review of recent advances

M Saleem, KA Shahzad, M Marryum, S Singh… - Stem Cell Research & …, 2024 - Springer
Exosomes, small extracellular vesicles secreted by cells, have emerged as focal mediators
in intercellular communication and therapeutic interventions across diverse biomedical …