[HTML][HTML] Artificial intelligence and early detection of pancreatic cancer: 2020 summative review

B Kenner, ST Chari, D Kelsen, DS Klimstra, SJ Pandol… - Pancreas, 2021 - journals.lww.com
Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …

Precision medicine in complex diseases—Molecular subgrouping for improved prediction and treatment stratification

Å Johansson, OA Andreassen, S Brunak… - Journal of internal …, 2023 - Wiley Online Library
Complex diseases are caused by a combination of genetic, lifestyle, and environmental
factors and comprise common noncommunicable diseases, including allergies …

A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories

D Placido, B Yuan, JX Hjaltelin, C Zheng, AD Haue… - Nature medicine, 2023 - nature.com
Pancreatic cancer is an aggressive disease that typically presents late with poor outcomes,
indicating a pronounced need for early detection. In this study, we applied artificial …

Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource

A Wood, R Denholm, S Hollings, J Cooper, S Ip… - bmj, 2021 - bmj.com
Objective To describe a novel England-wide electronic health record (EHR) resource
enabling whole population research on covid-19 and cardiovascular disease while ensuring …

Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study

V Kuan, S Denaxas, P Patalay, D Nitsch… - The Lancet Digital …, 2023 - thelancet.com
Background Globally, there is a paucity of multimorbidity and comorbidity data, especially for
minority ethnic groups and younger people. We estimated the frequency of common disease …

[HTML][HTML] COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records

JH Thygesen, C Tomlinson, S Hollings… - The Lancet Digital …, 2022 - thelancet.com
Background Updatable estimates of COVID-19 onset, progression, and trajectories underpin
pandemic mitigation efforts. To identify and characterise disease trajectories, we aimed to …

The promise of digital healthcare technologies

AWK Yeung, A Torkamani, AJ Butte… - Frontiers in Public …, 2023 - frontiersin.org
Digital health technologies have been in use for many years in a wide spectrum of
healthcare scenarios. This narrative review outlines the current use and the future strategies …

Disease trajectories and mortality among individuals diagnosed with depression: a community-based cohort study in UK Biobank

X Han, C Hou, H Yang, W Chen, Z Ying, Y Hu… - Molecular …, 2021 - nature.com
Patients with depression are at increased risk for a range of comorbid diseases, with,
however, unclear explanations. In this large community-based cohort study of the UK …

Longitudinal machine learning uncouples healthy aging factors from chronic disease risks

NM Cohen, A Lifshitz, R Jaschek, E Rinott, R Balicer… - Nature Aging, 2024 - nature.com
To understand human longevity, inherent aging processes must be distinguished from
known etiologies leading to age-related chronic diseases. Such deconvolution is difficult to …

The role of artificial intelligence in hypertensive disorders of pregnancy: towards personalized healthcare

M Alkhodari, Z Xiong, AH Khandoker… - Expert Review of …, 2023 - Taylor & Francis
Introduction Guidelines advise ongoing follow-up of patients after hypertensive disorders of
pregnancy (HDP) to assess cardiovascular risk and manage future patient-specific …