Drug reaction with eosinophilia and systemic symptoms (DReSS), also known as drug-
induced hypersensitivity syndrome (DiHS), is a severe, systemic, T cell mediated drug …

Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic
symptoms (DIHS/DRESS) is one example of a severe delayed T-cell–mediated adverse …

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN) is a predominantly drug-
induced disease, with a mortality rate of 15–20%, that engages the expertise of multiple …

Identification of CD8+ T cell epitopes is critical for the development of immunotherapeutics.
Existing methods for major histocompatibility complex class I (MHC class I) ligand discovery …

Delayed-type drug hypersensitivity reactions are major causes of morbidity and mortality.
The origin, phenotype, and function of pathogenic T cells across the spectrum of severity …

Drug allergy (DA) remains a complex and unaddressed problem worldwide that often
deprives patients of optimal medication choices and places them at risk for life‐threatening …

The drug allergy practice parameter was developed to provide guidance on the diagnosis
and management of drug hypersensitivity reactions. It was last updated in 2010. With the …

Idiosyncratic drug‐induced liver injury (DILI) remains an important clinical problem, both
during drug development and the prescription of a range of licensed drugs. Although rare …

Severe cutaneous adverse reactions (SCARs), which include Stevens–Johnson syndrome
and toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (also …

Drug-induced liver injury (DILI) is one of the serious adverse drug reactions (ADRs), which
belongs to immune-mediated adverse drug reactions (IM-ADRs). As an essential health …